Evidence map›Paper›PMID 29104476›Full record

ArticleInternational journal of medical sciences2017

GLP-1 Treatment Improves Diabetic Retinopathy by Alleviating Autophagy through GLP-1R-ERK1/2-HDAC6 Signaling Pathway.

Xiangsheng Cai, Jingjing Li, Mingzhu Wang, Miaoqin She, Yongming Tang, Jinlong Li, Hongwei Li, Hongxiang Hui

Open access · goldAbstract read
In one paragraph

Article in International journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Autophagy in ocular diseases: from mechanisms to therapeutic potential.Frontiers in cell and developmental biology · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Characterization of Vitreous Microbiota Dysbiosis Associated with Proliferative Diabetic Retinopathy.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Role of Autophagy in Type 2 Diabetes Mellitus: The Metabolic Clash.Journal of cellular and molecular medicine · 2024
    Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiangsheng CaiSchool of Biotechnology, Southern Medical University, Guangzhou 510515, China.
Jingjing LiSchool of Biotechnology, Southern Medical University, Guangzhou 510515, China.
Mingzhu WangSchool of Biotechnology, Southern Medical University, Guangzhou 510515, China.
Miaoqin SheSchool of Biotechnology, Southern Medical University, Guangzhou 510515, China.
Yongming TangUCLA Center for Excellence in Pancreatic Disease, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA.
Jinlong LiSchool of Biotechnology, Southern Medical University, Guangzhou 510515, China.
Hongwei LiSchool of Biotechnology, Southern Medical University, Guangzhou 510515, China.
Hongxiang HuiSchool of Biotechnology, Southern Medical University, Guangzhou 510515, China.
Southern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsApoptosisAutophagyBiomarkersDiabetes Mellitus, ExperimentalDiabetes Mellitus, Type 2Diabetic RetinopathyGlucagon-Like Peptide 1Glucagon-Like Peptide-1 ReceptorHistone Deacetylase 6MaleMAP Kinase Signaling SystemOxidative StressRatsRats, Sprague-DawleyReactive Oxygen SpeciesBiomarkersGlp1r protein, ratGlucagon-Like Peptide 1Glucagon-Like Peptide-1 ReceptorHDAC6 protein, ratHistone Deacetylase 6Reactive Oxygen SpeciesStreptozocinautophagyGLP-1HDAC6.oxidative stressretinopathy

Identifiers

PMID29104476
PMCPMC5666553
OpenAlexW2760610354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.