Evidence map›Paper›PMID 29104291›Full record

ReviewNature reviews. Neurology2018

A unifying motor control framework for task-specific dystonia.

Anna Sadnicka, Katja Kornysheva, John C Rothwell, Mark J Edwards

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 62 citations in OpenAlex.

  1. The relationship between occupation and specific forms of idiopathic adult-onset dystonia.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  2. Article
  3. Article
  4. Deep Phenotyping of Musicians' Upper Limb Dystonia.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025
    Article
  5. "Gol-Gappa" Dystonia - A Novel Form of Focal Task-Specific Dystonia.Tremor and other hyperkinetic movements (New York, N.Y.) · 2025
    Article
  6. Brain network pathophysiology in dystonia.Dystonia (Lausanne, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Basis of movement control in dystonia and why botulinum toxin should influence it?Toxicon : official journal of the International Society on Toxinology · 2024
    Article
  11. Article
  12. Article
  13. Practice behaviors as trigger factor for the onset of Musicians' Dystonia.Journal of neural transmission (Vienna, Austria : 1996) · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Dysfunctional Networks in Functional Dystonia.Advances in neurobiology · 2023
    Review
  18. Article
  19. Article
  20. Diagnostic Neurophysiologic Biomarkers for Task-Specific Dystonia.Movement disorders clinical practice · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Anna SadnickaSobell Department for Motor Neuroscience, Institute of Neurology, University College London, 33 Queen Square, London WC1N 3BG, UK, and the Motor Control and movement Disorders Group, St George's University of London, Cranmer Terrace, Tooting, London SW17 0RE, UK.
Katja KornyshevaSchool of Psychology, Bangor University, Adeilad Brigantia, Penrallt Road, Gwynedd LL57 2AS, Wales, UK, and the Institute of Cognitive Neuroscience, University College London, 17 Queen Square, London WC1N 3AZ, UK.
John C RothwellSobell Department for Motor Neuroscience, Institute of Neurology, University College London, 33 Queen Square, London WC1N 3BG, UK.
Mark J EdwardsMotor Control and Movement Disorders Group, St George's University of London, Cranmer Terrace, Tooting, London SW17 0RE, UK.
University College London · GBSt George's, University of London · GB

Funding

Wellcome Trust 098881
6 · The paper itself

Abstract

Task-specific dystonia is a movement disorder characterized by a painless loss of dexterity specific to a particular motor skill. This disorder is prevalent among writers, musicians, dancers and athletes. No current treatment is predictably effective, and the disorder generally ends the careers of affected individuals. Traditional disease models of dystonia have a number of limitations with regard to task-specific dystonia. We therefore discuss emerging evidence that the disorder has its origins within normal compensatory mechanisms of a healthy motor system in which the representation and reproduction of motor skill are disrupted. We describe how risk factors for task-specific dystonia can be stratified and translated into mechanisms of dysfunctional motor control. The proposed model aims to define new directions for experimental research and stimulate therapeutic advances for this highly disabling disorder.

Indexed as

Dystonic DisordersHumansLearningMotor Skills

Identifiers

PMID29104291
PMCPMC5975945
OpenAlexW2765387550

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.