Evidence map›Paper›PMID 29104234›Full record

ArticleCells2017

Dupuytren's and Ledderhose Diseases in a Family with LMNA-Related Cardiomyopathy and a Novel Variant in the ASTE1 Gene.

Michael V Zaragoza, Cecilia H H Nguyen, Halida P Widyastuti, Linda A McCarthy, Anna Grosberg

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Cells · 2024
    Article
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Michael V ZaragozaUCI Cardiogenomics Program, Department of Pediatrics, Division of Genetics & Genomics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA. mzaragoz@uci.edu.
Cecilia H H NguyenUCI Cardiogenomics Program, Department of Pediatrics, Division of Genetics & Genomics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA. cecilihn@uci.edu.
Halida P WidyastutiUCI Cardiogenomics Program, Department of Pediatrics, Division of Genetics & Genomics, School of Medicine, University of California, Irvine, Irvine, CA 92697, USA. hwidyast@uci.edu.
Linda A McCarthyDepartment of Biomedical Engineering and The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, Irvine, CA 92697, USA. mccarthl@uci.edu.
Anna GrosbergDepartment of Biomedical Engineering and The Edwards Lifesciences Center for Advanced Cardiovascular Technology, University of California, Irvine, Irvine, CA 92697, USA. grosberg@uci.edu.
University of California, Irvine · USEdwards Lifesciences (United States) · US

Funding

Cardiac Functional and Structural Implications of Lamin A/C MutationsR01HL129008 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GROSBERG, ANNA, ZARAGOZA, MICHAEL V · 2015 to 2019
$2.1M
NHLBI NIH HHS R01 HL129008
6 · The paper itself

Abstract

Dupuytren's disease (palmar fibromatosis) involves nodules in fascia of the hand that leads to flexion contractures. Ledderhose disease (plantar fibromatosis) is similar with nodules of the foot. While clinical aspects are well-described, genetic mechanisms are unknown. We report a family with cardiac disease due to a heterozygous

Indexed as

arrhythmiasASTE1 genecardiomyopathyDupuytren’s diseasefibromatosisgenetic susceptibilitylaminLedderhose diseaseLMNA gene

Identifiers

PMID29104234
PMCPMC5753070
OpenAlexW2766728968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.