ReviewVirus research2018
Metagenomics reshapes the concepts of RNA virus evolution by revealing extensive horizontal virus transfer.
Review in Virus research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
132 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Systematic Review of Phylogenetic Analysis Techniques for RNA Viruses Using Bioinformatics.International journal of molecular sciences · 2025Pooled it
- The origins and evolution of the RNA virome in land flora.Molecular plant · 2026Article
- ViralQC: a tool for assessing completeness and contamination of predicted viral contigs.Bioinformatics (Oxford, England) · 2026Article
- Virus Research Special Issue "Cross-kingdom infection by viruses".Virus research · 2026Article
- Mycoviruses against plant pathogenic fungi: current understanding and future avenues of their potential implication.Archives of microbiology · 2026Review
- Core virome shapes adaptation of a phytopathogenic fungus to climate and cropping patterns.The ISME journal · 2026Article
- RNA virome comparison between sylvatic and urban-interface mosquitoes from Southeastern Brazil.Frontiers in cellular and infection microbiology · 2026Article
- Discovery of novel viruses related to theVirus evolution · 2026Article
- Detection of bacterial gene expression elements on Tobacco mosaic virus RNA using cDNA analysis.PloS one · 2026Article
- Diversity and persistence of the RNA virome of Philaenus spumarius, the European vector of Xylella fastidiosa.Scientific reports · 2025Article
- Transmission of apple stem grooving virus (Capillovirus mali) to apple from the soil-borne fungus Fusarium solani.BMC plant biology · 2025Article
- A group of segmented viruses contains genome segments sharing homology with multiple viral taxa.Journal of virology · 2025Article
- Review
- Human Riboviruses: A Comprehensive Study.Journal of molecular evolution · 2025Review
- RNA Virus Discovery Sheds Light on the Virome of a Major Vineyard Pest, the European Grapevine Moth (Viruses · 2025Article
- Bioinformatic Identification of Viral Genomes from High-Throughput Metagenomic Sequencing Data.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Article
- Metagenomic Analyses of Water Samples of Two Urban Freshwaters in Berlin, Germany, Reveal New Highly Diverse Invertebrate Viruses.Microorganisms · 2024Article
- Endogenous nege-like viral elements in arthropod genomes reveal virus-host coevolution and ancient history of two plant virus families.Journal of virology · 2024Article
- Reexamining the Mycovirome ofViruses · 2024Article
72 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Virus metagenomics is a young research filed but it has already transformed our understanding of virus diversity and evolution, and illuminated at a new level the connections between virus evolution and the evolution and ecology of the hosts. In this review article, we examine the new picture of the evolution of RNA viruses, the dominant component of the eukaryotic virome, that is emerging from metagenomic data analysis. The major expansion of many groups of RNA viruses through metagenomics allowed the construction of substantially improved phylogenetic trees for the conserved virus genes, primarily, the RNA-dependent RNA polymerases (RdRp). In particular, a new superfamily of widespread, small positive-strand RNA viruses was delineated that unites tombus-like and noda-like viruses. Comparison of the genome architectures of RNA viruses discovered by metagenomics and by traditional methods reveals an extent of gene module shuffling among diverse virus genomes that far exceeds the previous appreciation of this evolutionary phenomenon. Most dramatically, inclusion of the metagenomic data in phylogenetic analyses of the RdRp resulted in the identification of numerous, strongly supported groups that encompass RNA viruses from diverse hosts including different groups of protists, animals and plants. Notwithstanding potential caveats, in particular, incomplete and uneven sampling of eukaryotic taxa, these highly unexpected findings reveal horizontal virus transfer (HVT) between diverse hosts as the central aspect of RNA virus evolution. The vast and diverse virome of invertebrates, particularly nematodes and arthropods, appears to be the reservoir, from which the viromes of plants and vertebrates evolved via multiple HVT events.
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