ArticleEpidemiology and infection2017
Emergence of the L phenotype in Group B Streptococci in the South of Ireland.
Article in Epidemiology and infection, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.
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Who cites it
7 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Global patterns of antibiotic resistance in group BFrontiers in microbiology · 2025Pooled it
- Pooled it
- Increasing Antimicrobial Resistance Profile Diversity of Colonizing Group BAnnals of laboratory medicine · 2026Article
- Serotype distribution, virulence factors, and antimicrobial resistance profiles of Streptococcus agalactiae (Group B Streptococcus) isolated from pregnant women in the Brazilian Amazon.BMC microbiology · 2025Article
- Whole-Genome Sequencing Analysis Revealed High Genomic Variability, Recombination Events and Mobile Genetic Elements inAntibiotics (Basel, Switzerland) · 2025Article
- Recent development and fighting strategies for lincosamide antibiotic resistance.Clinical microbiology reviews · 2024Review
- Association of sexually-transmitted infection and African-American race with Streptococcus agalactiae colonization in pregnancy.Antimicrobial resistance and infection control · 2020Article
Corrections and comments
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Authors and funding
4 authors.
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Abstract
Group B Streptococcal isolates (n = 235) from the South of Ireland were characterised by serotyping, antimicrobial susceptibility and determination of the phenotypic and genotypic mechanisms of resistance. Resistance to erythromycin and clindamycin was observed in 21·3% and 20·4% of the total population, respectively. The c-MLSB phenotype was the most common phenotype detected (62%), with ermB being the predominant genetic determinant, present in 84% of resistant isolates. The rare L phenotype was observed in 2·9% (n = 7) of isolates, four of which harboured the lsaC gene responsible for clindamycin resistance. Serotypes Ia, III and II were the most common amongst the entire study population (28·1%, 24·7% and 14%, respectively). Four of the seven L phenotype isolates were serotype III and two of these strains were confirmed as the hypervirulent clone, ST-17 and harboured the hvgA gene. This is the first documented case of the L phenotype in Ireland to date and the study findings emphasise the need for continued monitoring of antibiotic resistance and serotype distribution in GBS isolates from Ireland.
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