Evidence map›Paper›PMID 29103135›Full record

ArticleClinical and experimental nephrology2018

Association of adiposity with hemoglobin levels in patients with chronic kidney disease not on dialysis.

Hirokazu Honda, Kota Ono, Tadao Akizawa, Kosaku Nitta, Akira Hishida

Erratum issuedOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in Clinical and experimental nephrology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Association of Metabolic Syndrome and Hyperferritinemia in Patients at Cardiovascular Risk.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 1 country.

Hirokazu HondaDivision of Nephrology, Department of Medicine, Showa University Koto Toyosu Hospital, 5-1-38, Toyosu, Koto-ku, Tokyo, 135-8577, Japan. hondah@med.showa-u.ac.jp.
Kota OnoClinical Research and Medical Innovation Center, Hokkaido University Hospital, Sapporo, Japan.
Tadao AkizawaDivision of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Kosaku NittaFourth Department of Internal Medicine, Tokyo Women's Medical University, Tokyo, Japan.
Akira HishidaYaizu City Hospital, Yaizu, Japan.
Hokkaido University Hospital · JPShizuoka University of Welfare · JPShowa University · JPShowa University Koto Toyosu HospitalTokyo Women's Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the general population, adiposity influences erythropoiesis and iron metabolism. We aimed to assess the relationships between adiposity [estimated by body mass index (BMI) and abdominal circumference (AC)] and biomarkers of erythropoiesis in patients with chronic kidney disease (CKD) not on dialysis.

methodsA total of 2322 patients from the Chronic Kidney Disease Japan Cohort study were included. Patients were grouped according to BMI (low: < 18.5 kg/m

resultsMultivariate regression analysis of the 3 time-points showed that high BMI and large AC in male patients were significantly associated with higher hemoglobin levels. Hemoglobin levels were lower in female patients with low BMI and small AC than that in female patients with normal BMI and large AC, respectively; however, hemoglobin levels plateaued above a threshold of 25 kg/m

conclusionsBody composition appears to be associated with erythropoiesis; however, adiposity may be only associated with increased erythropoiesis in male patients. In addition, body composition does not appear to hamper iron metabolism in CKD patients not on dialysis.

Indexed as

AdiposityErythropoiesisAdultAgedBody Mass IndexC-Reactive ProteinErythropoietinFemaleFerritinsHemoglobinsHumansMaleMiddle AgedProspective StudiesRenal Insufficiency, ChronicTransferrinC-Reactive ProteinErythropoietinFerritinsHemoglobinsTransferrinAbdominal circumferenceBody mass indexErythropoiesisInflammationNutrition

Identifiers

PMID29103135
PMCPMC5956024
OpenAlexW2766618679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.