ReviewJournal of Alzheimer's disease : JAD2018
The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features.
Review in Journal of Alzheimer's disease : JAD, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 69 citations in OpenAlex.
- Comparing perceptions of chronic traumatic encephalopathy (CTE) across health care disciplines.PM & R : the journal of injury, function, and rehabilitation · 2026Article
- Cortical subpial aging-related tau astrogliopathy in older adult men who participated in youth amateur American-style football.Journal of neuropathology and experimental neurology · 2026Article
- Neurodegenerative mortality among National Football League Players.EClinicalMedicine · 2026Article
- High frequency head impact exposure changes hippocampal sharp-wave ripple architecture.PloS one · 2026Article
- CTE neuropathology alone is associated with dementia and cognitive symptoms.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Fluid biomarkers of chronic traumatic brain injury.Nature reviews. Neurology · 2024Review
- Brain pathology and symptoms linked to concussion history: beyond chronic traumatic encephalopathy.Brain communications · 2024Article
- Applying the Consensus Criteria for Traumatic Encephalopathy Syndrome Retrospectively to Case Studies of Boxers from the 20th Century.Neurotrauma reports · 2024Article
- Microglial activation persists beyond clinical recovery following sport concussion in collegiate athletes.Frontiers in neurology · 2023Article
- Chronic traumatic encephalopathy neuropathologic change is uncommon in men who played amateur American football.Frontiers in neurology · 2023Article
- A narrative review of psychiatric features of traumatic encephalopathy syndrome as conceptualized in the 20th century.Frontiers in neurology · 2023Review
- Tau as a fluid biomarker of concussion and neurodegeneration.Concussion (London, England) · 2022Review
- Defining traumatic encephalopathy syndrome - advances and challenges.Nature reviews. Neurology · 2021Article
- Association of Position Played and Career Duration and Chronic Traumatic Encephalopathy at Autopsy in Elite Football and Hockey Players.Neurology · 2021Article
- Broader Insights into Understanding Tumor Necrosis Factor and Neurodegenerative Disease Pathogenesis Infer New Therapeutic Approaches.Journal of Alzheimer's disease : JAD · 2021Review
- Symptoms of traumatic encephalopathy syndrome are common in the US general population.Brain communications · 2021Article
- Examining the Research Criteria for Traumatic Encephalopathy Syndrome in Middle-Aged Men From the General Population Who Played Contact Sports in High School.Frontiers in neurology · 2021Article
- Clinical and neuropsychological profile of patients with dementia and chronic traumatic encephalopathy.Journal of neurology, neurosurgery, and psychiatry · 2020Article
- Association between contact sports participation and chronic traumatic encephalopathy: a retrospective cohort study.Brain pathology (Zurich, Switzerland) · 2020Article
- Risk for Misdiagnosing Chronic Traumatic Encephalopathy in Men With Anger Control Problems.Frontiers in neurology · 2020Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
There is tremendous recent interest in chronic traumatic encephalopathy (CTE) in former collision sport athletes, civilians, and military veterans. This critical review places important recent research results into a historical context. In 2015, preliminary consensus criteria were developed for defining the neuropathology of CTE, which substantially narrowed the pathology previously reported to be characteristic. There are no agreed upon clinical criteria for diagnosis, although sets of criteria have been proposed for research purposes. A prevailing theory is that CTE is an inexorably progressive neurodegenerative disease within the molecular classification of the tauopathies. However, historical and recent evidence suggests that CTE, as it is presented in the literature, might not be pathologically or clinically progressive in a substantial percentage of people. At present, it is not known whether the emergence, course, or severity of clinical symptoms can be predicted by specific combinations of neuropathologies, thresholds for accumulation of pathology, or regional distributions of pathologies. More research is needed to determine the extent to which the neuropathology ascribed to long-term effects of neurotrauma is static, progressive, or both. Disambiguating the pathology from the broad array of clinical features that have been reported in recent studies might facilitate and accelerate research- and improve understanding of CTE.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.