ArticleIn vivo (Athens, Greece)
Functional Abnormalities and Thyroid Nodules in Patients with End-stage Renal Disease.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Understanding the Drivers of Hypothyroidism in Patients Undergoing Chronic Hemodialysis.Diagnostics (Basel, Switzerland) · 2026Article
- The role of the primary cilium in thyroid function and dysfunction with implications for thyroid disease.Histochemistry and cell biology · 2025Review
- Cross-section of thyroidology and nephrology: Literature review and key points for clinicians.Journal of clinical & translational endocrinology · 2024Review
- Incidence of thyroid nodules in early stage autosomal polycystic kidney disease.BMC nephrology · 2022Article
- Thyroid Pathology in End-Stage Renal Disease Patients on Hemodialysis.Diagnostics (Basel, Switzerland) · 2020Article
- Prevalence of Hypothyroidism among Dialysis Patients in Palestine: A Cross-Sectional Study.International journal of nephrology · 2020Article
- Phosphate binders as a cause of hypothyroidism in dialysis patients: practical indications from a review of the literature.BMC nephrology · 2018Review
- Benign nodules of the thyroid gland and 25-hydroxy-vitamin D levels in euthyroid patients.Annals of Saudi medicineArticle
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimClinical and subclinical hypothyroidism is more common in patients with end-stage renal disease (ESRD) than in the general population. Patients with ESRD with hypothyroidism are more susceptible to cardiovascular disease, with an increased risk of mortality than those with normal thyroid function. Moreover, these patients have higher incidence of benign and malignant nodules. PATIENTS AND
methodsThis was a retrospective study on 2,147 patients with ESRD on the renal transplant waiting list between 2000 and 2015 aimed at identifying the presence of hypothyroidism and associated variables.
resultsHypothyroidism was detected in 437/2,147 (20.3%) patients, 289 of them having the subclinical form. Cardiovascular disease and older age were significantly associated with hypothyroidism, and autosomal polycystic kidney disease was correlated to goiter (p<0.001).
conclusionThyroid abnormalities, particularly hypothyroidism with nodules, should be investigated in patients with ESRD on a waiting list for renal transplant to control cardiovascular complications and cancer risk.
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Registered trials
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