Evidence map›Paper›PMID 29102868›Full record

ArticleChild abuse & neglect2018

Associations of adversity in childhood and risk factors for cardiovascular disease in mid-adulthood.

Emma L Anderson, Abigail Fraser, Rishi Caleyachetty, Rebecca Hardy, Debbie A Lawlor, Laura D Howe

Abstract read
In one paragraph

Article in Child abuse & neglect, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
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  12. Childhood migration experience and adult health: evidence from China's rural migrants.Archives of public health = Archives belges de sante publique · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emma L AndersonMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; School of Social and Community Medicine, University of Bristol, Bristol, UK. Electronic address: emma.louise.anderson@bristol.ac.uk.
Abigail FraserMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; School of Social and Community Medicine, University of Bristol, Bristol, UK.
Rishi CaleyachettyThe Institute of Applied Health Research, University of Birmingham, UK.
Rebecca HardyMRC Unit for Lifelong Health and Ageing at University College London, UK.
Debbie A LawlorMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; School of Social and Community Medicine, University of Bristol, Bristol, UK.
Laura D HoweMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; School of Social and Community Medicine, University of Bristol, Bristol, UK.

Funding

Early life adversity and trajectories of cardiometabolic health, cognitive function and physical function: improving understanding of the mechanisms and potential reversibilityR01AG048835 · NIA · UNIVERSITY OF BRISTOL · PI HOWE, LAURA D · 2014 to 2015
$154k
British Heart Foundation SP/07/008/24066Medical Research Council G1001357Medical Research Council G9815508Medical Research Council MC_PC_15018Medical Research Council MC_UU_12013/5Medical Research Council MC_UU_12013/9Medical Research Council MC_UU_12019/1Medical Research Council MC_UU_12019/2Medical Research Council MR/M009351/1Medical Research Council MR/M020894/1Medical Research Council MR/P014437/1NIA NIH HHS R01 AG048835Wellcome TrustWellcome Trust 092731Wellcome Trust WT092830M
6 · The paper itself

Abstract

Studies assessing associations of childhood psychosocial adversity (e.g. sexual abuse, physical neglect, parental death), as opposed to socioeconomic adversity, with cardiovascular disease (CVD) risk factors in adulthood are scarce. The aim of this study is to assess associations of various types of psychosocial adversity and cumulative adversity in childhood, with multiple CVD risk factors in mid-life. At study enrolment, women from the Avon Longitudinal Study of Parents and Children (N=3612) retrospectively reported: lack of maternal care, maternal overprotection, parental mental illness, household dysfunction, sexual abuse, physical and emotional abuse, and neglect in childhood. Approximately 23 years later, body mass index (BMI), waist circumference, systolic and diastolic blood pressure, plasma glucose, insulin, triglycerides, low and high density lipoprotein cholesterol, C-reactive protein, carotid intima-media thickness (cIMT) and arterial distensibility were assessed (mean age 51 years). We examined associations of each specific type of psychosocial adversity and cumulative adversity with CVD risk factors. No specific type of psychosocial adversity was consistently associated with the CVD risk factors. There was evidence that a one standard deviation greater cumulative psychosocial adversity was associated with 0.51cm greater waist circumference (95% confidence interval [CI]: 0.02cm, 1.00cm, p=0.04) and a lower arterial distensibility, even after adjustment for age, ethnicity and childhood and adult socioeconomic position. We found no consistent evidence that any specific type of psychosocial adversity, or cumulative psychosocial adversity in childhood, is associated with CVD risk factors in adult women.

Indexed as

Adult Survivors of Child AbuseAdolescentAdultBody Mass IndexCardiovascular DiseasesCarotid Intima-Media ThicknessChildChild AbuseC-Reactive ProteinFemaleHumansLongitudinal StudiesMaleMental DisordersMiddle AgedRetrospective StudiesC-Reactive ProteinAdversityCardiovascular diseaseChildhoodPsychosocial

Identifiers

PMID29102868
PMCPMC5915314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.