Evidence map›Paper›PMID 29102664›Full record

ArticleNeuroscience2017

Atypical Callosal Morphology in Children with Speech Sound Disorder.

Eileen Luders, Florian Kurth, Lauren Pigdon, Gina Conti-Ramsden, Sheena Reilly, Angela T Morgan

Abstract read
In one paragraph

Article in Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Neuroimaging of the Syllable Repetition Task in Children With Residual Speech Sound Disorder.Journal of speech, language, and hearing research : JSLHR · 2021
    Article
  8. Article
  9. A Psycholinguistic Framework for Diagnosis and Treatment Planning of Developmental Speech Disorders.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Eileen LudersCousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, USA; Murdoch Childrens Research Institute, Melbourne, Australia. Electronic address: eileen.luders@ucla.edu.
Florian KurthCousins Center for Psychoneuroimmunology, Semel Institute for Neuroscience and Human Behavior, Department of Psychiatry and Biobehavioral Sciences, UCLA School of Medicine, Los Angeles, USA.
Lauren PigdonMurdoch Childrens Research Institute, Melbourne, Australia.
Gina Conti-RamsdenMurdoch Childrens Research Institute, Melbourne, Australia; The University of Manchester and Manchester Academic Health Science Centre (MAHSC), Manchester, United Kingdom.
Sheena ReillyMurdoch Childrens Research Institute, Melbourne, Australia; Menzies Health Institute at Griffith University, Gold Coast, Queensland, Australia.
Angela T MorganMurdoch Childrens Research Institute, Melbourne, Australia; University of Melbourne, Melbourne, Australia. Electronic address: angela.morgan@mcri.edu.au.

Funding

Brain and behavior in individuals with intersex conditionsR01HD081720 · NICHD · UNIVERSITY OF CAMBRIDGE · PI HINES, MELISSA, LUEDERS, EILEEN · 2015 to 2020
$1.8M
NICHD NIH HHS R01 HD081720
6 · The paper itself

Abstract

Speech sound disorder (SSD) is common, yet its neurobiology is poorly understood. Recent studies indicate atypical structural and functional anomalies either in one hemisphere or both hemispheres, which might be accompanied by alterations in inter-hemispheric connectivity. Indeed, abnormalities of the corpus callosum - the main fiber tract connecting the two hemispheres - have been linked to speech and language deficits in associated disorders, such as stuttering, dyslexia, aphasia, etc. However, there is a dearth of studies examining the corpus callosum in SSD. Here, we investigated whether a sample of 18 children with SSD differed in callosal morphology from 18 typically developing children carefully matched for age. Significantly reduced dimensions of the corpus callosum, particularly in the callosal anterior third, were observed in children with SSD. These findings indicating pronounced callosal aberrations in SSD make an important contribution to an understudied field of research and may suggest that SSD is accompanied by atypical lateralization of speech and language function.

Indexed as

AdolescentCase-Control StudiesChildCohort StudiesCorpus CallosumFemaleHumansImage Processing, Computer-AssistedLanguage Development DisordersMagnetic Resonance ImagingMaleSpeech Sound Disorderanterior thirdbraincorpus callosumdevelopmentlanguagemagnetic resonance imaging

Identifiers

PMID29102664
PMCPMC5709239

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.