ArticleThe American journal of cardiology2017
Relation of Changes in Body Fat Distribution to Oxidative Stress.
Article in The American journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 42 citations in OpenAlex.
- Effects of Two Moderate-Intensity Aerobic Exercise Prescriptions on Inflammatory Cytokines and Oxidative Stress Biomarkers in Obese Hispanic Females.International journal of molecular sciences · 2026Trial
- The Association Between Total and Regional Body Fat and Bone Mineral Content in Young Athletes: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Visceral Adipose Tissue Cut Points for Increased Metabolic Risk in Chinese Adults Using Low-Dose Computed Tomography: A Nationwide Multicenter Study.Obesity facts · 2026Article
- Article
- Association of Android and Gynoid Fatness With Incident Dementia and Brain Structure.Journal of cachexia, sarcopenia and muscle · 2025Article
- Article
- Associations of Ultra-Processed Food Intake with Body Fat and Skeletal Muscle Mass by Sociodemographic Factors.Diabetes & metabolism journal · 2024Article
- Intermittent Fasting: Myths, Fakes and Truth on This Dietary Regimen Approach.Foods (Basel, Switzerland) · 2024Review
- Review
- Inflammatory and Oxidative Stress Biomarkers in the Elderly, the Birjand Longitudinal Aging Study.BioMed research international · 2023Article
- Methylenetetrahydrofolate Reductase C677T Gene Variant in Relation to Body Mass Index and Folate Concentration in a Polish Population.Biomedicines · 2022Article
- Randomized controlled trial for time-restricted eating in overweight and obese young adults.iScience · 2022Article
- Obesity Is Associated with Sustained Symptomatology and Unique Inflammatory Features in Children with Asthma.The journal of allergy and clinical immunology. In practice · 2022Article
- Epicardial Adipose Tissue and Cardiac Arrhythmias: Focus on Atrial Fibrillation.Frontiers in cardiovascular medicine · 2022Review
- Positive association of unhealthy plant-based diets with the incidence of abdominal obesity in Korea: a comparison of baseline, most recent, and cumulative average diets.Epidemiology and health · 2022Article
- Central adiposity increases the odds for plasma folate deficiency among Chinese women of reproductive age.Frontiers in public health · 2022Article
- Untargeted metabolomics reveals plasma metabolites predictive of ectopic fat in pancreas and liver as assessed by magnetic resonance imaging: the TOFI_Asia study.International journal of obesity (2005) · 2021Article
- Vascular Regenerative Capacity and the Obesity Paradox in Coronary Artery Disease.Arteriosclerosis, thrombosis, and vascular biology · 2021Article
- Contribution of Adipose Tissue Oxidative Stress to Obesity-Associated Diabetes Risk and Ethnic Differences: Focus on Women of African Ancestry.Antioxidants (Basel, Switzerland) · 2021Review
- Low folate intake and serum levels are associated with higher body mass index and abdominal fat accumulation: a case control study.Nutrition journal · 2020Article
Corrections and comments
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Authors and funding
17 authors at 2 institutions in 1 country.
Funding
Abstract
Android fat is a surrogate measure of visceral obesity in the truncal region. Both visceral adiposity and oxidative stress (OS) are linked to cardiometabolic risk factors and clinical cardiovascular disease. However, whether body fat distribution (android vs gynoid) is associated with OS remains unknown. We hypothesized that increased android fat will be associated with greater OS. Body fat distribution and markers of OS, including plasma levels of reduced (cysteine and glutathione) and oxidized (cystine and glutathione disulfide) aminothiols, were estimated in 711 volunteers (67% female, 23% black, mean age 48 ± 11) enrolled in the Emory Georgia Tech Predictive Health study. At 1 year, 498 subjects had repeat testing. At baseline, anthropometric and fat distribution indexes, including body mass index, waist circumference, weight/hip ratio, and android and gynoid fat mass correlated with lower plasma concentrations of glutathione and higher cystine levels indicative of higher OS. At 1 year, the change in android but not gynoid fat mass or body mass index negatively correlated with the change in the plasma glutathione level after adjustment for cardiovascular risk factors. Increased body fat, specifically android fat mass, is an independent determinant of systemic OS, and its change is associated with a simultaneous change in OS, measured as plasma glutathione. In conclusion, our findings suggest that excess android or visceral fat contributes to the development of cardiovascular disease through modulating OS.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.