ArticleClinical rheumatology2018
Red blood cell distribution width: a potential laboratory parameter for monitoring inflammation in rheumatoid arthritis.
Article in Clinical rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
62 citing papers in PubMed, 1 synthesis or guideline pooled it, 94 citations in OpenAlex.
- Pooled it
- Effect of curcumin on inflammatory biomarkers and iron profile in patients with premenstrual syndrome and dysmenorrhea: A randomized controlled trial.Physiological reports · 2023Trial
- Elevated red cell distribution width as a prognostic indicator in critically ill patients with atrial fibrillation and chronic kidney disease.BMC cardiovascular disorders · 2026Article
- Establishment of a Charlson comorbidity index-based model for predicting the preterm premature rupture of the membrane.Translational pediatrics · 2026Article
- Article
- Hemoglobin-to-Red Cell Distribution Width Ratio and Vitamin D Status as Early Predictors of Cardiovascular Risk in Primary Sjögren's Syndrome.Life (Basel, Switzerland) · 2026Article
- The Association Between Platelet Indices and Osteoarthritis: A Systematic Review and Meta-analysis.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2026Article
- Red Cell Distribution Width to Albumin Ratio: A Novel and Potential Biomarker for Rheumatoid Arthritis.Journal of inflammation research · 2026Article
- Red cell distribution width-to-albumin ratio as a potential biomarker for short-term mortality risk in critically ill patients with cerebral hemorrhage: a retrospective study with dual-cohort validation.Frontiers in nutrition · 2026Article
- Continuation of Statins after Acute Intracerebral Haemorrhage and Survival: The Role of Inflammation, Infection, and Indication Bias.Cerebrovascular diseases (Basel, Switzerland) · 2026Article
- Causal Interplay Between Platelet Indices and Rheumatoid Arthritis: Genetic Evidence From Bidirectional Mendelian Randomization.International journal of genomics · 2026Article
- Association Between Hemoglobin-to-Red Blood Cell Distribution Width Ratio and Arterial Stiffness.Journal of clinical hypertension (Greenwich, Conn.) · 2025Article
- Association of Red Cell Distribution Width and Red-Cell-Distribution-Width-to-Albumin Ratio with Cardiovascular Diseases in Postmenopausal Women: A Cross-Sectional Study based on the National Health and Nutrition Examination Survey 2003-2016.Anatolian journal of cardiology · 2025Article
- Hemoglobin-to-Red Cell Distribution Width Ratio Was Associated with Cardiovascular Diseases and Death.Journal of clinical medicine · 2025Article
- Red cell distribution width as a potential new biomarker to predict the clinical severity of acute diverticulitis.BMC gastroenterology · 2025Article
- The Red Cell Distribution Width-to-Albumin Ratio Predicts 1-Year Mortality in Patients with Chronic Obstructive Pulmonary Disease: Evidence From MIMIC-IV and NHANES.International journal of chronic obstructive pulmonary disease · 2025Article
- Association between the hemoglobin-to-red cell distribution width ratio and three-month unfavorable outcome in older acute ischemic stroke patients: a prospective study.Frontiers in neurology · 2025Article
- SARS-CoV-2 ORF8 drives osteoclastogenesis in preexisting immune-mediated inflammatory diseases.JCI insight · 2024Article
- Novel immunoinflammatory blood markers in Graves' orbitopathy: insights into activity and severity.BMJ open ophthalmology · 2024Article
- Analysis of hsa_circ_0136256 as a biomarker for fibrosis in systemic sclerosis.BMC biotechnology · 2024Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Correlation analysis of red blood cell distribution width (RDW) and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), tumor necrosis factor α (TNF-α), interleukin (IL)-6, and IL-10 in rheumatoid arthritis (RA) to investigate whether RDW can serve as a potential parameter for indicating inflammation in RA patients. A total of 670 RA patients from October 2014 to April 2016 were enrolled in our study. The white blood cell (WBC), red blood cell (RBC), platelet (PLT), hemoglobin (HGB), RDW, CRP, and ESR in peripheral blood of patients with RA were retrospectively analyzed. The relative expression of TNF-α, IL-6, and IL-10 was detected by RT-qPCR. Correlation analysis between RDW and CRP, ESR, TNF-α, IL-6, and IL-10 in RA was conducted by Microsoft Excel. RDW level was significantly increased in RA patients compared to osteoarthritis (OA) patients (P < 0.001) and healthy donors (HDs) (P < 0.001), and RDW was positively associated with inflammatory markers, such as CRP and ESR. In ROC curve analysis, the area under the curve (AUC) of RDW for the identification of RA was 0.881, with a 95% confidence interval (CI) from 0.864 to 0.898. Moreover, correlation analysis showed that RDW level was positively associated with TNF-α and IL-6, however negatively associated with IL-10. RDW was increased in patients with RA which was associated with inflammation in RA, suggesting that RDW may be a potential auxiliary marker for indicating inflammation process in RA conveniently.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.