ArticlePrevention science : the official journal of the Society for Prevention Research2019
Personalizing and Optimizing Preventive Intervention Models via a Translational Neuroscience Framework.
Article in Prevention science : the official journal of the Society for Prevention Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- The Physiological Regulation of Emotion During Social Interactions: Vagal Flexibility Moderates the Effects of a Military Parenting Intervention on Father Involvement in a Randomized Trial.Prevention science : the official journal of the Society for Prevention Research · 2020Trial
- Addressing Health Disparities through Community Engagement in Artificial Intelligence-Driven Prevention Science.Prevention science : the official journal of the Society for Prevention Research · 2026Review
- Protocol to study neurobiological pathways to adverse patterns of substance use in adolescents with anxiety.Addiction neuroscience · 2026Article
- The Youth Risk Index: psychometrics, predicting the initiation of early adolescent substance use, and the breadth of liability detected.Frontiers in child and adolescent psychiatry · 2025Article
- Practical, Economic, and Policy Implications of the Leve et al. Paper.Prevention science : the official journal of the Society for Prevention Research · 2024Article
- The Promise and Challenges of Integrating Biological and Prevention Sciences: A Community-Engaged Model for the Next Generation of Translational Research.Prevention science : the official journal of the Society for Prevention Research · 2024Article
- Normalization of Prevention Principles and Practices to Reduce Substance Use Disorders Through an Integrated Dissemination and Implementation Framework.Prevention science : the official journal of the Society for Prevention Research · 2023Review
- Early experience unpredictability in child development as a model for understanding the impact of the COVID-19 pandemic: A translational neuroscience perspective.Developmental cognitive neuroscience · 2022Article
- Stress Coping Strategies as Mediators: Toward a Better Understanding of Sexual, Substance, and Delinquent Behavior-Related Risk-Taking among Transition-Aged Youth.Deviant behavior · 2022Article
- Commentary on the Culture of Prevention.Prevention science : the official journal of the Society for Prevention Research · 2021Article
- Cultural Adaptation of Promising, Evidence-Based, and Best Practices: a Scoping Literature Review.Prevention science : the official journal of the Society for Prevention Research · 2020Article
- The Neurosciences of Health Communication: An fNIRS Analysis of Prefrontal Cortex and Porn Consumption in Young Women for the Development of Prevention Health Programs.Frontiers in psychology · 2020Article
- Levers and barriers to success in the use of translational neuroscience for the prevention and treatment of mental health and promotion of well-being across the lifespan.Journal of abnormal psychology · 2020Article
- Precision Strategies as a Timely and Unifying Framework for Ongoing Prevention Science Advances.Prevention science : the official journal of the Society for Prevention Research · 2019Article
- Moving Toward a Precision-Based, Personalized Framework for Prevention Science: Introduction to the Special Issue.Prevention science : the official journal of the Society for Prevention Research · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A new generation of research, building upon developmental psychopathology (Luthar et al. 1997; Luthar et al. (Child Development, 71, 543-562, 2000)), provides evidence that individual differences in risk for behavioral health problems result from intrapersonal and environmental modulation of neurophysiologic and genetic substrates. This transdisciplinary model suggests that, in any given individual, the number of genetic variants implicated in high-risk behavior and the way in which they are assorted and ultimately suppressed or activated in the brain by experiential and contextual factors help to explain behavioral orientations. Implications are that behavioral health problems can be amplified or reduced based on characteristics of an individual and socio-contextual influences on those characteristics. This emerging research has extraordinary implications for the design of prevention programs that more precisely target the malleable mechanisms that underlie behavioral health problems and, hence, more effectively prevent behavioral problems and promote resilience. A detailed, theory-driven examination of all evidence-based interventions is called for to identify the active ingredients that specifically impact these underlying mechanisms. Such an approach will enhance the ability of preventive interventions to achieve effect sizes indicative of beneficial impacts for a greater number of recipients. This paper presents the significant implications of this collective knowledge base for the next generation of precision-based, prevention-focused personalized interventions.
Indexed as
Identifiers
29101644What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.