Evidence map›Paper›PMID 29101346›Full record

ArticleScientific reports2017

Development and Validation of a Multi-Algorithm Analytic Platform to Detect Off-Target Mechanical Ventilation.

Jason Y Adams, Monica K Lieng, Brooks T Kuhn, Greg B Rehm, Edward C Guo, Sandra L Taylor, Jean-Pierre Delplanque, Nicholas R Anderson

Abstract readValidation Study
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. PVADet: fast patient-ventilator asynchrony detection on waveforms.Journal of clinical monitoring and computing · 2026
    Article
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Artificial intelligence in respiratory care.Frontiers in digital health · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Artificial Intelligence in the Intensive Care Unit.Critical care (London, England) · 2020
    Review
  12. Review
  13. Observational
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jason Y AdamsDivision of Pulmonary, Critical Care, and Sleep Medicine, University of California Davis, Sacramento, CA, USA. jyadams@ucdavis.edu.ORCID 0000-0001-5623-8702
Monica K LiengSchool of Medicine, University of California Davis, Sacramento, CA, USA.
Brooks T KuhnDivision of Pulmonary, Critical Care, and Sleep Medicine, University of California Davis, Sacramento, CA, USA.
Greg B RehmDepartment of Computer Science, University of California Davis, Davis, CA, USA.
Edward C GuoDepartment of Computer Science, University of California Davis, Davis, CA, USA.
Sandra L TaylorDepartment of Public Health Sciences, Division of Biostatistics, University of California Davis, Davis, CA, USA.
Jean-Pierre DelplanqueDepartment of Mechanical and Aerospace Engineering, University of California Davis, Davis, CA, USA.
Nicholas R AndersonDepartment of Public Health Sciences, Division of Informatics, University of California Davis, Davis, CA, USA.

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
DANGER: Developing the Next Generation of Emergency Medicine ResearchersK12HL108964 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HOLMES, JAMES F., KUPPERMANN, NATHAN · 2011 to 2015
$3.1M
NCATS NIH HHS UL1 TR001860NHLBI NIH HHS K12 HL108964
6 · The paper itself

Abstract

Healthcare-specific analytic software is needed to process the large volumes of streaming physiologic waveform data increasingly available from life support devices such as mechanical ventilators. Detection of clinically relevant events from these data streams will advance understanding of critical illness, enable real-time clinical decision support, and improve both clinical outcomes and patient experience. We used mechanical ventilation waveform data (VWD) as a use case to address broader issues of data access and analysis including discrimination between true events and waveform artifacts. We developed an open source data acquisition platform to acquire VWD, and a modular, multi-algorithm analytic platform (ventMAP) to enable automated detection of off-target ventilation (OTV) delivery in critically-ill patients. We tested the hypothesis that use of artifact correction logic would improve the specificity of clinical event detection without compromising sensitivity. We showed that ventMAP could accurately detect harmful forms of OTV including excessive tidal volumes and common forms of patient-ventilator asynchrony, and that artifact correction significantly improved the specificity of event detection without decreasing sensitivity. Our multi-disciplinary approach has enabled automated analysis of high-volume streaming patient waveform data for clinical and translational research, and will advance the study and management of critically ill patients requiring mechanical ventilation.

Indexed as

AlgorithmsRespiration, ArtificialVentilators, MechanicalCritical IllnessHumansIntensive Care UnitsSoftwareTidal Volume

Identifiers

PMID29101346
PMCPMC5670237

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.