Evidence map›Paper›PMID 29101248›Full record

ArticleEndocrine connections2017

Increased circulating interleukin-8 in patients with resistance to thyroid hormone receptor α.

Anne H van der Spek, Olga V Surovtseva, Saskia Aan, Anton T J Tool, Annemarie van de Geer, Korcan Demir, Anja L M van Gucht, A S Paul van Trotsenburg, Timo K van den Berg, Eric Fliers and 1 more

Open access · goldAbstract read
In one paragraph

Article in Endocrine connections, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. The Clinical Spectrum of Resistance to Thyroid Hormone Alpha in Children and AdultsJournal of clinical research in pediatric endocrinology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Anne H van der SpekDepartment of Endocrinology and MetabolismAcademic Medical Center, Amsterdam, The Netherlands.
Olga V SurovtsevaDepartment of Endocrinology and MetabolismAcademic Medical Center, Amsterdam, The Netherlands.
Saskia AanDepartment of Endocrinology and MetabolismAcademic Medical Center, Amsterdam, The Netherlands.
Anton T J ToolSanquin Research and Landsteiner LaboratoryAcademic Medical Center, Amsterdam, The Netherlands.
Annemarie van de GeerSanquin Research and Landsteiner LaboratoryAcademic Medical Center, Amsterdam, The Netherlands.
Korcan DemirDivision of Pediatric EndocrinologyDokuz Eylül University, Izmir, Turkey.
Anja L M van GuchtDepartment of EndocrinologyErasmus Medical Center, Rotterdam, The Netherlands.
A S Paul van TrotsenburgDepartment of Pediatric EndocrinologyAcademic Medical Center, Amsterdam, The Netherlands.
Timo K van den BergSanquin Research and Landsteiner LaboratoryAcademic Medical Center, Amsterdam, The Netherlands.
Eric FliersDepartment of Endocrinology and MetabolismAcademic Medical Center, Amsterdam, The Netherlands.
Anita BoelenDepartment of Endocrinology and MetabolismAcademic Medical Center, Amsterdam, The Netherlands a.boelen@amc.uva.nl.
Academic Medical Center · NLSanquin · NLDokuz Eylül University · TRErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Innate immune cells have recently been identified as novel thyroid hormone (TH) target cells in which intracellular TH levels appear to play an important functional role. The possible involvement of TH receptor alpha (TRα), which is the predominant TR in these cells, has not been studied to date. Studies in TRα

Indexed as

innate immunityinterleukin-8macrophageneutrophilresistance to thyroid hormonethyroid hormone receptor alpha

Identifiers

PMID29101248
PMCPMC5670275
OpenAlexW2765689948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.