Evidence map›Paper›PMID 29101237›Full record

ArticleBlood2018

Human

Yueying Li, Chen Jin, Hao Bai, Yongxing Gao, Shu Sun, Lei Chen, Lei Qin, Paul P Liu, Linzhao Cheng, Qian-Fei Wang

Open access · bronzeAbstract read
In one paragraph

Article in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. N2B27 media formulations influence gastruloid development.Development (Cambridge, England) · 2025
    Article
  5. ABlood vessels, thrombosis & hemostasis · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Notch signaling pathway: architecture, disease, and therapeutics.Signal transduction and targeted therapy · 2022
    Review
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Yueying LiKey Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Chen JinKey Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Hao BaiDivision of Hematology, Department of Medicine and.
Yongxing GaoDivision of Hematology, Department of Medicine and.
Shu SunKey Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Lei ChenKey Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Lei QinKey Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Paul P LiuTranslational and Functional Genomics Branch, National Institutes of Health, National Human Genome Research Institute, Bethesda, MD.
Linzhao ChengDivision of Hematology, Department of Medicine and.
Qian-Fei WangKey Laboratory of Genomic and Precision Medicine, Collaborative Innovation Center of Genetics and Development, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.
Chinese Academy of Sciences · CNBeijing Institute of Genomics · CNJohns Hopkins Medicine · USJohns Hopkins University · USNational Human Genome Research Institute · USUniversity of Chinese Academy of Sciences · CN

Funding

GENETIC ANALYSIS OF ZEBRAFISH EMBRYO DEVELOPMENTZIAHG000102 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI LIU, PAUL · 2009 to 2025
$17.1M
Genetically enhanced human erythrocytes generated from expandable stem cellsR01HL130676 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI CHENG, LINZHAO · 2015 to 2018
$2.0M
NHLBI NIH HHS R01 HL130676
6 · The paper itself

Abstract

Megakaryocytes (MKs) in adult marrow produce platelets that play important roles in blood coagulation and hemostasis. Monoallelic mutations of the master transcription factor gene

Indexed as

Gene Expression Regulation, DevelopmentalThrombopoiesisCell LineCell ProliferationCore Binding Factor Alpha 2 SubunitCRISPR-Cas SystemsHumansInduced Pluripotent Stem CellsMegakaryocytesPoint MutationReceptor, Notch4Signal TransductionCore Binding Factor Alpha 2 SubunitNOTCH4 protein, humanReceptor, Notch4RUNX1 protein, human

Identifiers

PMID29101237
PMCPMC5757696
OpenAlexW2737038364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.