Evidence map›Paper›PMID 29101210›Full record

ArticleScience immunology2017

Candidalysin sets off the innate alarm.

Xin Li, Irina Leonardi, Iliyan D Iliev

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Science immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Xin LiDivision of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.ORCID 0000-0002-9444-8214
Irina LeonardiDivision of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA.ORCID 0000-0002-0369-7371
Iliyan D IlievDivision of Gastroenterology and Hepatology, Joan and Sanford I. Weill Department of Medicine, Weill Cornell Medicine, Cornell University, New York, NY 10021, USA. iliev@med.cornell.edu.ORCID 0000-0003-0884-9749
Cornell University · US

Funding

Commensal fungal communities in the regulation of immunity and intestinal inflammation.R01DK113136 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ILIYAN Dimitrov ILIEV · 2017 to 2026
$4.2M
Mechanisms of Protection by Commensal Fungi in ColitisR00DK098310 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI ILIEV, ILIYAN DIMITROV · 2016 to 2018
$729k
Impact of immunosuppression therapy on commensal fungi and intestinal diseaseR21AI123819 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI ILIEV, ILIYAN DIMITROV · 2016 to 2017
$466k
Mechanisms of Protection by Commensal Fungi in ColitisK99DK098310 · NIDDK · CEDARS-SINAI MEDICAL CENTER · PI ILIEV, ILIYAN DIMITROV · 2014 to 2015
$180k
NIAID NIH HHS R21 AI123819NIDDK NIH HHS K99 DK098310NIDDK NIH HHS R00 DK098310NIDDK NIH HHS R01 DK113136
6 · The paper itself

Abstract

Candidalysin-induced epithelial cell damage promotes expansion of innate TCRαβ

Indexed as

Candida albicansFungal ProteinsEpithelial CellsVirulence FactorsECE1 protein, Candida albicansFungal ProteinsVirulence Factors

Identifiers

PMID29101210
PMCPMC6309692
OpenAlexW2765915919

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.