ArticleScience immunology2017
Oral epithelial cells orchestrate innate type 17 responses to
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Article in Science immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers.
0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed
11.7field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
140 citing papers in PubMed, 197 citations in OpenAlex.
- Efficacy of Cochleated Amphotericin B in Mouse and Human Mucocutaneous Candidiasis.Antimicrobial agents and chemotherapy · 2022Trial
- A dysbiotic microbiome triggers TScience translational medicine · 2018Trial
- IL-1 family signalling drives mucosal defence against systemic Candida albicans infection.Nature microbiology · 2026Article
- Candidalysin promotes fungal-specific Th17 CD4 T cell differentiation and protective systemic immunogenicity.Mucosal immunology · 2026Article
- Type 2 diabetes mellitus exacerbates vaginal group BmSphere · 2026Article
- Dangerous liaisons: Candidalysin and myeloid cells in candidiasis.PLoS pathogens · 2026Article
- An IL-17-DUOX2 axis controls gastrointestinal colonization by Candida albicans.Nature communications · 2026Article
- An IL-1, IL-17, and IL-22 cytokine circuit controls vulvovaginal candidiasis independently of estrogen.PLoS pathogens · 2026Article
- Non-canonical IL‑22 receptor signaling remodels the oral mucosal barrier during Candida albicans immunosurveillance.Nature communications · 2026Article
- Soluble Sema4D From γδ T Cells Exerts Osteoblast Inhibition via Plexin-B/mTOR Signalling Contributing to Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaws.Cell proliferation · 2026Article
- Article
- Article
- Fungal infection drives metabolic reprogramming in epithelial cells via aerobic glycolysis and an alternative TCA cycle shunt.Science advances · 2026Article
- Taste Dysfunction in Oral Candidiasis: Impact of Candida Carriage and Hyphal Presence.Mycoses · 2026Article
- Review
- The gut-liver-immune axis: structural basis, cellular architecture, molecular mediators, and disease-specific manifestations.Frontiers in immunology · 2026Review
- Fluconazole tolerance is associated with altered extracellular vesicle-mediated epithelial immune responses inFrontiers in microbiology · 2026Article
- Candidalysin at the epithelial-systemic interface: mechanistic evidence, critical-care relevance, and translational opportunities in invasive candidiasis.Frontiers in cellular and infection microbiology · 2026Review
- Article
- Dynamic expression of candidalysin facilitates oral colonization of Candida albicans in mice.Nature microbiology · 2025Article
80 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
16 authors at 5 institutions in 3 countries.
Akash H VermaDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0002-5985-5201
Jonathan P RichardsonMucosal and Salivary Biology Division, Dental Institute, King's College London, London, UK.
Chunsheng ZhouDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0002-9721-7948
Bianca M ColemanDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0003-4276-7456
David L MoyesMucosal and Salivary Biology Division, Dental Institute, King's College London, London, UK.ORCID 0000-0002-1657-918X
Jemima HoMucosal and Salivary Biology Division, Dental Institute, King's College London, London, UK.ORCID 0000-0002-2356-9190
Anna R HupplerDepartment of Pediatrics, Children's Research Institute, Children's Hospital and Health System, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
Kritika RamaniDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Mandy J McGeachyDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Ilgiz A MufazalovInstitute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University of Mainz, Mainz, Germany.ORCID 0000-0001-9332-0131
Ari WaismanInstitute for Molecular Medicine, University Medical Center of the Johannes Gutenberg University of Mainz, Mainz, Germany.ORCID 0000-0003-4304-8234
Lawrence P KaneDepartment of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0001-5198-516X
Partha S BiswasDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Bernhard HubeDepartment of Microbial Pathogenicity Mechanisms, Leibniz Institute for Natural Product Research and Infection Biology-Hans Knoell Institute, Jena, Germany.ORCID 0000-0002-6028-0425
Julian R NaglikMucosal and Salivary Biology Division, Dental Institute, King's College London, London, UK. sarah.gaffen@pitt.edu julian.naglik@kcl.ac.uk.ORCID 0000-0002-8072-7917
Sarah L GaffenDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA. sarah.gaffen@pitt.edu julian.naglik@kcl.ac.uk.ORCID 0000-0001-8511-2041
University of Pittsburgh · USKing's College London · GBJohannes Gutenberg University Mainz · DEChildren's Hospital of Wisconsin · USJena University Hospital · DE
Funding
Host and Fungal Regulation of Type 17 Immunity to Oral CandidiasisR37DE022550 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Sarah L Gaffen · 2017 to 2026
$5.6MBiochemical and Spatial Regulation of IKKg/NEMO During T Cell ActivationR01AI103022 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUNNELL, STEPHEN C, KANE, LAWRENCE P. · 2013 to 2017
$3.0MIL-17 Receptor Signaling in the Oral MucosaR01DE022550 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GAFFEN, SARAH L · 2012 to 2016
$2.1MIL-23/STAT3-Driven Oral Immune Responses to Candida albicansR01DE023815 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GAFFEN, SARAH L · 2014 to 2018
$1.9MNegative Control of IL-17R Signaling: Implications for Fungal ImmunityR01AI107825 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GAFFEN, SARAH L · 2014 to 2018
$1.9MRegulation of Th17 Functions in Autoimmune CNS InflammationR01AI110822 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MCGEACHY, MANDY J · 2015 to 2019
$1.7MMechanisms of IL-17 Mediated Host Defense in the KidneyR01DK104680 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BISWAS, PARTHA SARATHI · 2015 to 2019
$1.5MAnti-Candida activity of CCL28 in oropharyngeal candidiasisK08DE026189 · NIDCR · MEDICAL COLLEGE OF WISCONSIN · PI HUPPLER, ANNA · 2017 to 2021
$860kSpecial BD LSRFortessaTMS10OD011925 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BORGHESI, LISA · 2012 to 2012
$383kRegulation of Th17 Functions in Autoimmune CNS InflammationR56AI110822 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MCGEACHY, MANDY J · 2014 to 2014
$369kBiotechnology and Biological Sciences Research Council BB/N014677/1Medical Research Council MR/M011372/1NIAID NIH HHS R01 AI103022NIAID NIH HHS R01 AI107825NIAID NIH HHS R01 AI110822NIAID NIH HHS R56 AI110822NIDCR NIH HHS K08 DE026189NIDCR NIH HHS R01 DE023815NIDCR NIH HHS R37 DE022550NIDDK NIH HHS R01 DK104680NIH HHS S10 OD011925
Abstract
PubMed holds no abstract for this paper.
Indexed as
Adaptive ImmunityAnimalsCandida albicansCandidiasisCytokinesEpithelial CellsFemaleFungal ProteinsHumansHyphaeImmunity, InnateInterleukin-17MaleMice, Inbred C57BLMice, KnockoutMice, TransgenicCytokinesECE1 protein, Candida albicansFungal ProteinsInterleukin-17Virulence Factors
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.