Evidence map›Paper›PMID 29101102›Full record

ArticleBritish journal of sports medicine2018

Prevalence of knee pain, radiographic osteoarthritis and arthroplasty in retired professional footballers compared with men in the general population: a cross-sectional study.

Gwen Sascha Fernandes, Sanjay Mukund Parekh, Jonathan Moses, Colin Fuller, Brigitte Scammell, Mark Edward Batt, Weiya Zhang, Michael Doherty

Registry-linked trialAbstract read
In one paragraph

Article in British journal of sports medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04956393 (Proof-of-Concept of the SOAR), which is not on this map. Cited by 49 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04956393 nacompletednot on this mapstarted 2021, after this paper: background citation

Proof-of-Concept of the SOAR (Stop OsteoARthritis) Program: A Randomized Delayed-Control Trial

TypeinterventionalSponsorUniversity of British ColumbiaRan2021 to 2023Enrolled58ConditionsArthritis, Osteoarthritis, Arthritis Knee, Osteo Arthritis KneeArmsImmediate 8-Week SOAR Program, Delayed 8-Week SOAR Program
3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. MicroRNA expression in osteoarthritis: a meta-analysis.Clinical and experimental medicine · 2023
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Two-year follow-up of varus progression in young professional football players.BMC sports science, medicine & rehabilitation · 2026
    Article
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  7. Article
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  13. Analysis of Genu Varum in Young Male Professional Soccer Players.Orthopaedic journal of sports medicine · 2025
    Article
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  15. Article
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  17. Review
  18. Article
  19. Femoral cartilage ultrasound echo-intensity is a valid measure of cartilage composition.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Gwen Sascha FernandesDivision of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, UK.
Sanjay Mukund ParekhDivision of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, UK.ORCID http://orcid.org/0000-0002-4249-0891
Jonathan MosesDivision of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, UK.
Colin FullerArthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Queens Medical Centre, Nottingham, UK.
Brigitte ScammellDivision of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, UK.
Mark Edward BattDivision of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, UK.
Weiya ZhangDivision of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, UK.
Michael DohertyDivision of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham City Hospital, Nottingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo determine the prevalence of knee pain, radiographic knee osteoarthritis (RKOA), total knee replacement (TKR) and associated risk factors in male ex-professional footballers compared with men in the general population (comparison group).

methods1207 male ex-footballers and 4085 men in the general population in the UK were assessed by postal questionnaire. Current knee pain was defined as pain in or around the knees on most days of the previous month. Presence and severity of RKOA were assessed on standardised radiographs using the Nottingham Line Drawing Atlas (NLDA) in a subsample of 470 ex-footballers and 491 men in the comparison group. The adjusted risk ratio (aRR) and adjusted risk difference (aRD) with 95% CI in ex-footballers compared with the general population were calculated using the marginal model in Stata.

resultsEx-footballers were more likely than the comparison group to have current knee pain (aRR 1.91, 95% CI 1.77 to 2.06), RKOA (aRR 2.21, 95% CI 1.92 to 2.54) and TKR (aRR 3.61, 95% CI 2.90 to 4.50). Ex-footballers were also more likely to present with chondrocalcinosis (aRR 3.41, 95% CI 2.44 to 4.77). Prevalence of knee pain and RKOA were higher in ex-footballers at all ages. However, even after adjustment for significant knee injury and other risk factors, there was more than a doubling of risk of these outcomes in footballers.

conclusionsThe prevalence of all knee osteoarthritis outcomes (knee pain, RKOA and TKR) were two to three times higher in male ex-footballers compared with men in the general population group. Knee injury is the main attributable risk factor. Even after adjustment for recognised risk factors, knee osteoarthritis appear to be an occupational hazard of professional football.

Indexed as

AthletesAgedArthroplastyArthroplasty, Replacement, KneeAthletic InjuriesCross-Sectional StudiesHumansKnee JointMaleMiddle AgedOsteoarthritis, KneePainPrevalenceRadiographyRetirementRisk Factorsepidemiologyfootballosteoarthritis

Identifiers

PMID29101102
PMCPMC5931242

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.