Evidence map›Paper›PMID 29100838›Full record

ArticleJournal of neuroscience methods2018

ALICE: A tool for automatic localization of intra-cranial electrodes for clinical and high-density grids.

Mariana P Branco, Anna Gaglianese, Daniel R Glen, Dora Hermes, Ziad S Saad, Natalia Petridou, Nick F Ramsey

Registry-linked trialAbstract readValidation Study
In one paragraph

Article in Journal of neuroscience methods, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04479410 (Efficient Automated Localization of ECoG Electrodes in CT Images Via Shape Analysis), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04479410 completednot on this mapstarted 2020, after this paper: background citation

Efficient Automated Localization of ECoG Electrodes in CT Images Via Shape Analysis

TypeobservationalSponsorNeuromed IRCCSRan2020 to 2020Enrolled24ConditionsElectrodes Recognition Ability
3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  16. Efficient automated localization of ECoG electrodes in CT images via shape analysis.International journal of computer assisted radiology and surgery · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mariana P BrancoDepartment of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center, The Netherlands.
Anna GaglianeseDepartment of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center, The Netherlands; Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Daniel R GlenScientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, United States.
Dora HermesDepartment of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center, The Netherlands; Department of Psychology, New York University, New York, NY, United States; Department of Psychology, Stanford University, Stanford, CA, United States.
Ziad S SaadScientific and Statistical Computing Core, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892, United States.
Natalia PetridouDepartment of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.
Nick F RamseyDepartment of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center, The Netherlands. Electronic address: N.F.Ramsey@umcutrecht.nl.

Funding

Scientific and Statistical Computing CoreZICMH002888 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI TAYLOR, PAUL · 2009 to 2025
$30.9M
Development and validation of empirical models of the neuronal population activity underlying non-invasive human brain measurementsR01MH111417 · NIMH · UNIVERSITY MEDICAL CENTER UTRECHT · PI DEVINSKY, ORRIN, DIJKHUIZEN, RICK M · 2016 to 2020
$4.4M
NIMH NIH HHS R01 MH111417
6 · The paper itself

Abstract

backgroundElectrocorticographic (ECoG) measurements require the accurate localization of implanted electrodes with respect to the subject's neuroanatomy. Electrode localization is particularly relevant to associate structure with function. Several procedures have attempted to solve this problem, namely by co-registering a post-operative computed tomography (CT) scan, with a pre-operative magnetic resonance imaging (MRI) anatomy scan. However, this type of procedure requires a manual and time-consuming detection and transcription of the electrode coordinates from the CT volume scan and restricts the extraction of smaller high-resolution ECoG grid electrodes due to the downsampling of the CT. NEW

methodALICE automatically detects electrodes on the post-operative high-resolution CT scan, visualizes them in a combined 2D and 3D volume space using AFNI and SUMA software and then projects the electrodes on the individual's cortical surface rendering. The pipeline integrates the multiple-step method into a user-friendly GUI in Matlab

resultsALICE was validated in 13 subjects implanted with clinical ECoG grids by comparing the calculated electrode center-of-mass coordinates with those computed using a commonly used method. COMPARISON WITH EXISTING

methodsA novel aspect of ALICE is the combined 2D-3D visualization of the electrodes on the CT scan and the option to also detect high-density ECoG grids. Feasibility was shown in 5 subjects and validated for 2 subjects.

conclusionsThe ALICE pipeline provides a fast and accurate detection, discrimination and localization of ECoG electrodes spaced down to 4 mm apart.

Indexed as

Electrodes, ImplantedTomography, X-Ray ComputedAdolescentAdultCerebral CortexChildDrug Resistant EpilepsyElectrocorticographyFemaleHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMaleMiddle AgedPattern Recognition, AutomatedSoftwareALICEClinical gridECoGElectrode localizationHigh-density gridIntegrated pipeline

Identifiers

PMID29100838
PMCPMC5952625

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.