Evidence map›Paper›PMID 29100550›Full record

Trial reportTrials2017

Effects of a liquefied petroleum gas stove intervention on pollutant exposure and adult cardiopulmonary outcomes (CHAP): study protocol for a randomized controlled trial.

Magdalena Fandiño-Del-Rio, Dina Goodman, Josiah L Kephart, Catherine H Miele, Kendra N Williams, Mitra Moazzami, Elizabeth C Fung, Kirsten Koehler, Victor G Davila-Roman, Kathryn A Lee and 6 more

2 registry-linked trialsAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Trials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02994680 nacompletednot on this map

Effects of a Liquefied Petroleum Gas Stove and Fuel Distribution Intervention on Adult Cardiopulmonary Health Outcomes in Puno, Peru

TypeinterventionalSponsorJohns Hopkins Bloomberg School of Public HealthRan2017 to 2019Enrolled181ConditionsBlood Pressure, Carotid Intima Media Thickness, Endothelial Function, Signs and Symptoms, RespiratoryArmsThree-burner LPG stove, Delivery of LPG tanks, Vouchers for LPG tanks
NCT05524987 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Addressing HyperteNsion and Diabetes Through Community-Engaged Systems in Puno, Peru (ANDES Study)

TypeinterventionalSponsorUniversidad Peruana Cayetano HerediaRan2023 to 2026Enrolled1,068ConditionsHypertension, DiabetesArmsANDES INTERVENTION
3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  14. Voucher-based liquefied petroleum gas subsidies achieve nearly exclusive clean fuel use when affordable delivery is available.Energy for sustainable development : the journal of the International Energy Initiative · 2025
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  17. Sustained use of liquefied petroleum gas following one year of free fuel and behavioral support in Puno, Peru.Energy for sustainable development : the journal of the International Energy Initiative · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Magdalena Fandiño-Del-RioDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St. Room 555, Baltimore, MD, 21205, USA.
Dina GoodmanDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St. Room 555, Baltimore, MD, 21205, USA.
Josiah L KephartDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St. Room 555, Baltimore, MD, 21205, USA.
Catherine H MieleDepartment of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Kendra N WilliamsDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St. Room 555, Baltimore, MD, 21205, USA.
Mitra MoazzamiDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St. Room 555, Baltimore, MD, 21205, USA.
Elizabeth C FungDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St. Room 555, Baltimore, MD, 21205, USA.
Kirsten KoehlerDepartment of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Victor G Davila-RomanCardiovascular Division, Department of Medicine, Washington University, St. Louis, MO, USA.
Kathryn A LeeDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St. Room 555, Baltimore, MD, 21205, USA.
Saachi NangiaDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St. Room 555, Baltimore, MD, 21205, USA.
Steven A HarveyDepartment of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Kyle SteenlandDepartment of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Gustavo F GonzalesDepartment of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Lima, Peru.
William CheckleyDivision of Pulmonary and Critical Care, School of Medicine, Johns Hopkins University, 1830 E. Monument St. Room 555, Baltimore, MD, 21205, USA. wcheckl1@jhmi.edu.ORCID http://orcid.org/0000-0003-1106-8812
Cardiopulmonary outcomes and Household Air Pollution trial (CHAP) Trial Investigators

Funding

Traning Program in Environmental Health SciencesT32ES007141 · NIEHS · JOHNS HOPKINS UNIVERSITY · PI Marsha Wills-Karp · 1985 to 2026
$22.2M
UJMT – ORWH – Gazzetta, Issa-BoubeD43TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI William Checkley, Benjamin H. Chi · 2017 to 2026
$14.8M
Building U.S. Research Capacity Through International Environmental Health Science on Air Pollution, Cardiorespiratory Disease, and Alzheimer’s Disease (Research U01)U01TW010107 · FIC · UNIVERSIDAD PERUANA CAYETANO HEREDIA · PI William Checkley, Stella Maria Hartinger · 2015 to 2026
$3.5M
GEOHealth Hub Peru: Building U.S. Research Capacity Through International Environmental Health Science on Air Pollution, Cardiorespiratory Disease, and Alzheimer’s Disease (Research Training U2R)U2RTW010114 · FIC · EMORY UNIVERSITY · PI William Checkley, Stella Maria Hartinger · 2015 to 2026
$3.3M
FIC NIH HHS D43 TW009340FIC NIH HHS U01 TW010107FIC NIH HHS U2R TW010114NIEHS NIH HHS T32 ES007141
6 · The paper itself

Abstract

backgroundBiomass fuel smoke is a leading risk factor for the burden of disease worldwide. International campaigns are promoting the widespread adoption of liquefied petroleum gas (LPG) in resource-limited settings. However, it is unclear if the introduction and use of LPG stoves, in settings where biomass fuels are used daily, reduces pollution concentration exposure, improves health outcomes, or how cultural and social barriers influence the exclusive adoption of LPG stoves.

methodsWe will conduct a randomized controlled, field intervention trial of LPG stoves and fuel distribution in rural Puno, Peru, in which we will enroll 180 female participants aged 25-64 years and follow them for 2 years. After enrollment, we will collect information on sociodemographic characteristics, household characteristics, and cooking practices. During the first year of the study, LPG stoves and fuel tanks will be delivered to the homes of 90 intervention participants. During the second year, participants in the intervention arm will keep their LPG stoves, but the gas supply will stop. Control participants will receive LPG stoves and vouchers to obtain free fuel from distributors at the beginning of the second year, but gas will not be delivered. Starting at baseline, we will collect longitudinal measurements of respiratory symptoms, pulmonary function, blood pressure, endothelial function, carotid artery intima-media thickness, 24-h dietary recalls, exhaled carbon monoxide, quality-of-life indicators, and stove-use behaviors. Environmental exposure assessments will occur six times over the 2-year follow-up period, consisting of 48-h personal exposure and kitchen concentration measurements of fine particulate matter and carbon monoxide, and 48-h kitchen concentrations of nitrogen dioxide for a subset of 100 participants. DISCUSSION: Findings from this study will allow us to better understand behavioral patterns, environmental exposures, and cardiovascular and pulmonary outcomes resulting from the adoption of LPG stoves. If this trial indicates that LPG stoves are a feasible and effective way to reduce household air pollution and improve health, it will provide important information to support widespread adoption of LPG fuel as a strategy to reduce the global burden of disease.

trial registrationClinicalTrials.gov, ID: NCT02994680 , Cardiopulmonary Outcomes and Household Air Pollution (CHAP) Trial. Registered on 28 November 2016.

Indexed as

Household ArticlesAdultAir Pollution, IndoorCardiovascular SystemCookingEnvironmental MonitoringEquipment DesignFemaleGasesHeart DiseasesHousingHumansInhalation ExposureLungLung DiseasesMiddle AgedGasesPetroleumBehavior changeBiomass fuelCardiopulmonary outcomesCookstoveExclusive adoptionHousehold air pollutionIndoor air pollutionLPGPersonal exposure

Identifiers

PMID29100550
PMCPMC5670728

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.