ArticleSouthern medical journal2017
Subclinical Atherosclerosis Among Young and Middle-Aged Adults Using Carotid Intima-Media Thickness Measurements.
Article in Southern medical journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Association of Intima-Media Thickness Measured at the Common Carotid Artery With Incident Carotid Plaque: Individual Participant Data Meta-Analysis of 20 Prospective Studies.Journal of the American Heart Association · 2023Pooled it
- Carotid intima-media thickness predicts carotid plaque development: Meta-analysis of seven studies involving 9341 participants.European journal of clinical investigation · 2020Pooled it
- Predicting cardiovascular risk using a novel risk score in young and middle-age adults with HIV: associations with biomarkers and carotid atherosclerotic plaque.International journal of STD & AIDS · 2022Article
- Correlation of Carotid Artery Intima-Media Thickness with Calcium and Phosphorus Metabolism, Parathyroid Hormone, Microinflammatory State, and Cardiovascular Disease.BioMed research international · 2022Article
- Heart Health and Behavior Change in HIV-Infected Individuals.AIDS and behavior · 2021Article
- The association of HIV and cocaine use to cigarette smoking in the context of depression and perceived stress.AIDS care · 2020Article
- HIV and carotid atherosclerosis: a mediational model.AIDS care · 2020Article
- The Role of Mitochondria in Cardiovascular Diseases.Biology · 2020Review
- A model to predict unstable carotid plaques in population with high risk of stroke.BMC cardiovascular disorders · 2020Article
- Effect of bariatric surgery on flow-mediated dilation and carotid intima-media thickness in patients with morbid obesity: 1-year follow-up study.Anatolian journal of cardiology · 2020Article
- Effect of cigarette smoking on carotid artery atherosclerosis: a community-based cohort study.Heart and vessels · 2020Article
- Relationships Between Ion Channels, Mitochondrial Functions and Inflammation in Human Aging.Frontiers in physiology · 2019Review
- Blood Pressure, HIV, and Cocaine Use Among Ethnically and Racially Diverse Individuals.Southern medical journal · 2018Article
- Measurement invariance of the Childhood Trauma Questionnaire by gender, poverty level, and HIV status.Personalized medicine in psychiatryArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
objectivesThe presence of atherosclerotic plaque in the carotid arteries is a strong predictor of cardiovascular disease (CVD). Research and data on CVD risk have been derived primarily from individuals aged 55 years or older, and assessment of CVD risk among young and middle-aged adults seldom has been studied. The use of ultrasonography to measure carotid intima-media thickness (IMT) and carotid plaque appears to have utility to detect subclinical atherosclerosis in asymptomatic adults. This study evaluated the presence of carotid plaque using ultrasonography among healthy young and middle-aged adults.
methodsParticipants were men and women recruited in Miami, Florida, and were 18 to 50 years old with no history of CVD. Participants underwent a general physical examination and carotid artery ultrasonography to evaluate carotid IMT and carotid plaque.
resultsFrom a total of 173 participants with a mean age of 34 years (standard deviation 8.9), 21.0% (95% confidence interval [CI] 15.0-27.2) were identified as having carotid plaque. IMT values ranged from 0.49 to 1.03 mm, with a mean value of 0.70 mm (standard deviation 0.09). In multivariable logistic regression older age (adjusted odds ratio [AOR] 1.08, 95% CI 1.01-1.16,
conclusionsTraditional CVD risk factors such as those evaluated in this study may fail to provide adequate predictive value of carotid atherosclerosis in younger populations with no history of CVD, because the majority of traditional risk factors identified in previous research were not associated with carotid plaque in this young sample. Further research assessing nontraditional risk factors among asymptomatic individuals is required, and the evaluation of IMT as an intervention tool to detect CVD risk in these asymptomatic populations is warranted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.