ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2017
Outbreak of chikungunya virus in a vulnerable population of Sergipe, Brazil-A molecular and serological survey.
Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Multisectoral Approach to Address Chikungunya Outbreaks Driven by Human Mobility: A Systematic Review and Meta-Analysis.The Journal of infectious diseases · 2020Pooled it
- Systems analysis of subjects acutely infected with the Chikungunya virus.PLoS pathogens · 2019Trial
- Circulation of chikungunya virus East/Central/South African lineage in Rio de Janeiro, Brazil.PloS one · 2019Trial
- B-cell epitope mapping of Orthoflavivirus zikaense in mother-newborn immune interaction reveals postnatal immune signatures.Scientific reports · 2025Article
- Revisiting the emergence of the Chikungunya virus in Alagoas, Northeast of Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Molecular characterization of Chikungunya virus recovered from patients in the Maranhão state, Brazil.Molecular biology reports · 2024Article
- Cryptic circulation of chikungunya virus in São Jose do Rio Preto, Brazil, 2015-2019.PLoS neglected tropical diseases · 2024Article
- Beyond Borders: Investigating the Mysteries of Cacipacoré, a Lesser-Studied Arbovirus in Brazil.Viruses · 2024Article
- Global Prevalence of Zika and Chikungunya Coinfection: A Systematic Review and Meta-Analysis.Diseases (Basel, Switzerland) · 2024Review
- Chikungunya virus infection in the southernmost state of Brazil was characterised by self-limited transmission (2017-2019) and a larger 2021 outbreak.Memorias do Instituto Oswaldo Cruz · 2023Article
- Article
- Persistence of chikungunya ECSA genotype and local outbreak in an upper medium class neighborhood in Northeast Brazil.PloS one · 2020Article
- Genome sequencing reveals coinfection by multiple chikungunya virus genotypes in a recent outbreak in Brazil.PLoS neglected tropical diseases · 2019Article
- Genomic, epidemiological and digital surveillance of Chikungunya virus in the Brazilian Amazon.PLoS neglected tropical diseases · 2019Article
- Granzyme A in Chikungunya and Other Arboviral Infections.Frontiers in immunology · 2019Article
- Circulation of Chikungunya virus East-Central-South Africa genotype during an outbreak in 2016-17 in Piaui State, Northeast Brazil.Revista do Instituto de Medicina Tropical de Sao Paulo · 2019Article
- Detection of East/Central/South African genotype Chikungunya virus during an outbreak in a southeastern state of Brazil.Epidemiology and infection · 2018Article
- Molecular and Clinical Characterization of Chikungunya Virus Infections in Southeast Mexico.Viruses · 2018Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundChikungunya virus (CHIKV) is a re-emerging arbovirus that is causing outbreaks in several countries of the Americas. The virus was introduced in Brazil in 2014, and since then, several Brazilian states have notified autochthonous cases.
objectivesProvide additional evidence on a CHIKV outbreak and an outline of the laboratory and clinical profile of symptomatic patients in Sergipe, Brazil. STUDY
designIn February 2016, we collected 142 serum samples from symptomatic patients for arboviruses in Sergipe, Brazil. All samples were submitted to qRT-PCR for the emerging arboviruses circulating in Brazil - ZIKV, CHIKV, and DENV - and later submitted to the immunoenzymatic assay. RNA positive samples were randomly selected and sequenced for characterization of the genotype involved in the outbreak.
resultsOur study had 75.35% (107/142) positivity for CHIKV infection, with all age groups and genera being equally infected. The virus was identified in 11 of the 13 cities studied in that state, including the ECSA genotype. Importantly, fever was the only statistically significant symptoms for CHIKV infection (p<0.05), while asthenia was significantly associated with symptomatic patients that were CHIKV-negative (p<0.05).
conclusionsOur findings support the importance of fever as a clinical marker and contribute to molecular and serological surveillance data, which may help in the understanding of CHIKV circulation, emergence and clinical description.
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