Evidence map›Paper›PMID 29100006›Full record

ArticleCell stem cell2017

Location, Location, Location: Spatio-Temporal Cues That Define the Cell of Origin in Melanoma.

Maria S Soengas, E Elizabeth Patton

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell stem cell, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. A deep learning-clinical nomogram hybrid for predicting sentinel lymph node metastasis in melanoma.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Melanoma Risk and Melanocyte Biology.Acta dermato-venereologica · 2020
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Maria S SoengasMelanoma Laboratory, Molecular Oncology Programme, Spanish National Cancer Research Center (CNIO), 28029 Madrid, Spain. Electronic address: msoengas@cnio.es.
E Elizabeth PattonMRC Institute of Genetics and Molecular Medicine, MRC Human Genetics Unit and University of Edinburgh Cancer Research UK Centre, Western General Hospital, EH4 2XR Edinburgh, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is unclear whether melanoma initiates from mature melanocytes or stem cell precursors. In this issue of Cell Stem Cell, Moon et al. (2017) and Köhler et al. (2017) use in vivo lineage tracing to demonstrate that these two possibilities may occur downstream of the same pro-tumorigenic lesions, depending on environmental factors or the anatomical location.

Indexed as

MelanomaSkin NeoplasmsCuesHumansMelanocytesStem Cells

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.