Evidence map›Paper›PMID 29099918›Full record

ArticlePathogens and disease2017

Draft genome sequence of the Wolbachia endosymbiont of Wuchereria bancrofti wWb.

Matthew Chung, Scott T Small, David Serre, Peter A Zimmerman, Julie C Dunning Hotopp

Open access · bronzeAbstract read
In one paragraph

Article in Pathogens and disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Fexinidazole and Corallopyronin A targetbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Matthew ChungInstitute for Genome Sciences, University of Maryland, Baltimore, MD 21201, USA.
Scott T SmallCenter for Global Health and Diseases, Case Western Reserve University, Cleveland, OH 44106, USA.
David SerreInstitute for Genome Sciences, University of Maryland, Baltimore, MD 21201, USA.
Peter A ZimmermanCenter for Global Health and Diseases, Case Western Reserve University, Cleveland, OH 44106, USA.
Julie C Dunning HotoppInstitute for Genome Sciences, University of Maryland, Baltimore, MD 21201, USA.
University of Maryland, Baltimore · USCenter for Global Health · US

Funding

Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI DUNNING HOTOPP, JULIE · 2014 to 2023
$36.5M
TRAINING IN GEOGRAPHIC MEDICINE &INFECTIOUS DISEASET32AI007024 · NIAID · CASE WESTERN RESERVE UNIVERSITY · PI KAZURA, JAMES WALTER · 1985 to 2020
$4.5M
NIAID NIH HHS T32 AI007024NIAID NIH HHS U19 AI110820
6 · The paper itself

Abstract

The draft genome assembly of the Wolbachia endosymbiont of Wuchereria bancrofti (wWb) consists of 1060 850 bp in 100 contigs and contains 961 ORFs, with a single copy of the 5S rRNA, 16S rRNA and 23S rRNA and each of the 34 tRNA genes. Phylogenetic core genome analyses show wWb to cluster with other strains in supergroup D of the Wolbachia phylogeny, while being most closely related to the Wolbachia endosymbiont of Brugia malayi strain TRS (wBm). The wWb and wBm genomes share 779 orthologous clusters with wWb having 101 unclustered genes and wBm having 23 unclustered genes. The higher number of unclustered genes in the wWb genome likely reflects the fragmentation of the draft genome.

Indexed as

Genome, BacterialSequence Analysis, DNAAnimalsCluster AnalysisGenes, rRNAOpen Reading FramesPhylogenyRNA, Ribosomal, 16SRNA, Ribosomal, 23SRNA, Ribosomal, 5SWolbachiaWuchereria bancroftiRNA, Ribosomal, 16SRNA, Ribosomal, 23SRNA, Ribosomal, 5Sendosymbiontgenomicslymphatic filariasisnematodeWolbachiaWuchereria bancrofti

Identifiers

PMID29099918
PMCPMC5827699
OpenAlexW2767170458

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.