Evidence map›Paper›PMID 29099913›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018

Trends in the San Francisco Human Immunodeficiency Virus Epidemic in the "Getting to Zero" Era.

Susan Scheer, Ling Hsu, Sandra Schwarcz, Sharon Pipkin, Diane Havlir, Susan Buchbinder, Nancy A Hessol

Abstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

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  19. Getting to Zero San Francisco: A Collective Impact Approach.Journal of acquired immune deficiency syndromes (1999) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Susan ScheerHIV Epidemiology Section, San Francisco Department of Public Health.
Ling HsuHIV Epidemiology Section, San Francisco Department of Public Health.
Sandra SchwarczHIV Epidemiology Section, San Francisco Department of Public Health.
Sharon PipkinHIV Epidemiology Section, San Francisco Department of Public Health.
Diane HavlirDepartment of Medicine, University of California.
Susan BuchbinderDepartment of Medicine, University of California.
Nancy A HessolDepartment of Medicine, University of California.

Funding

Virology CoreP30AI027763 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI STEVEN Grant DEEKS · 1988 to 2026
$93.6M
San Francisco Vaccine and Prevention UnitUM1AI069496 · NIAID · PUBLIC HEALTH FOUNDATION ENTERPRISES · PI Susan Buchbinder, Diane V Havlir · 2012 to 2026
$30.5M
National HIV Surveillance System (NHSS)U62PS004022 · PS · SAN FRANCISCO DEPARTMENT OF PUBLIC HEALTH · PI SCHEER, SUSAN · 2013 to 2016
$4.2M
NCHHSTP CDC HHS U62 PS004022NIAID NIH HHS P30 AI027763NIAID NIH HHS UM1 AI069496
6 · The paper itself

Abstract

Background: San Francisco has launched interventions to reduce new human immunodeficiency virus (HIV) infections and HIV-associated morbidity and mortality during the San Francisco "Getting to Zero" era. We measured recent changes in HIV care indicators to assess the success of these interventions. Methods: San Francisco residents with newly diagnosed HIV infection, diagnosed from 2009 to 2014, were included. We measured temporal changes from HIV diagnosis to (1) linkage to care in within ≤3 months, (2) initiation of antiretroviral therapy (ART) within ≤12 months, (3) viral suppression within ≤12 months, (4) development of AIDS within ≤3 months, (5) death within ≤12 months, and (6) retention in care 6-12 months after linkage. Kaplan-Meier analyses stratified by year of HIV diagnosis measured time from diagnosis to linkage, ART initiation, viral suppression, AIDS, and death. Results: Overall, the number of new diagnoses declined from 473 in 2009 to 329 in 2014. The proportion of new diagnoses among men (P = .005), Latinos and Asian/Pacific Islanders (P = .02), and men who have sex with men (P = .003) increased. ART initiation and viral suppression ≤12 months after diagnosis increased (P < .001), while the proportion with AIDS diagnosed ≤3 months after HIV diagnosis declined (P < .001). Time to ART initiation and time to viral suppression were significantly shorter in more recent years of diagnosis (P < .001). Time from HIV to AIDS diagnosis was significantly longer in more recent years (P < .001). Retention in care did not significantly change. Conclusions: In San Francisco new HIV diagnoses have declined and HIV care indicators have improved during the Getting to Zero era. Continued success requires attention to vulnerable populations and monitoring to adjust programmatic priorities.

Indexed as

Acquired Immunodeficiency SyndromeAdolescentAdultAnti-HIV AgentsDisease EradicationEpidemicsEpidemiological MonitoringFemaleHIV InfectionsHomosexuality, MaleHumansMaleMiddle AgedRisk FactorsSan FranciscoSexual and Gender MinoritiesAnti-HIV Agents

Identifiers

PMID29099913
PMCPMC6248750

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.