Evidence map›Paper›PMID 29099614›Full record

ArticleAnnals of the American Thoracic Society2018

Blood Leukocyte Concentrations, FEV

Rachel Zeig-Owens, Ankura Singh, Thomas K Aldrich, Charles B Hall, Theresa Schwartz, Mayris P Webber, Hillel W Cohen, Kerry J Kelly, Anna Nolan, David J Prezant and 1 more

Abstract read
In one paragraph

Article in Annals of the American Thoracic Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
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  10. Article
  11. Extracellular Vesicle-Encapsulated microRNAs as Novel Biomarkers of Lung Health.American journal of respiratory and critical care medicine · 2023
    Article
  12. Article
  13. Review
  14. Observational
  15. Review
  16. Serum Th-2 cytokines and FEVAmerican journal of industrial medicine · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Rachel Zeig-Owens1 The Bureau of Health Services and Office of Medical Affairs, Fire Department of the City of New York, Brooklyn, New York.
Ankura Singh1 The Bureau of Health Services and Office of Medical Affairs, Fire Department of the City of New York, Brooklyn, New York.
Thomas K Aldrich2 Division of Pulmonary Medicine, Department of Medicine, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, New York.
Charles B Hall4 Division of Biostatistics, Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York; and.
Theresa Schwartz1 The Bureau of Health Services and Office of Medical Affairs, Fire Department of the City of New York, Brooklyn, New York.
Mayris P Webber1 The Bureau of Health Services and Office of Medical Affairs, Fire Department of the City of New York, Brooklyn, New York.
Hillel W Cohen3 Division of Epidemiology and.
Kerry J Kelly1 The Bureau of Health Services and Office of Medical Affairs, Fire Department of the City of New York, Brooklyn, New York.
Anna Nolan1 The Bureau of Health Services and Office of Medical Affairs, Fire Department of the City of New York, Brooklyn, New York.
David J Prezant1 The Bureau of Health Services and Office of Medical Affairs, Fire Department of the City of New York, Brooklyn, New York.
Michael D Weiden1 The Bureau of Health Services and Office of Medical Affairs, Fire Department of the City of New York, Brooklyn, New York.

Funding

Core-010UL1TR001073 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI KELLER, MARLA J, SHAMOON, HARRY · 2013 to 2017
$21.3M
Metabolomics of World Trade Center-Lung Injury: Biomarker Validation, Longitudinal Assessment and Dietary InterventionU01OH011300 · OH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NOLAN, ANNA · 2017 to 2025
$4.8M
RAGE Mediates LPA Induced Pulmonary InflammationR01HL119326 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NOLAN, ANNA · 2015 to 2019
$2.1M
Evolution of Risk Factors for Sinusitis in WTC Exposed FirefightersU01OH010726 · OH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEIDEN, MICHAEL D. · 2014 to 2015
$1.9M
Evolution of risk factors for lung function decline in WTC exposed firefightersU01OH011302 · OH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI WEIDEN, MICHAEL D. · 2016 to 2018
$1.5M
NCATS NIH HHS UL1 TR001073NHLBI NIH HHS R01 HL119326NIOSH CDC HHS U01 OH010726NIOSH CDC HHS U01 OH011300NIOSH CDC HHS U01 OH011302
6 · The paper itself

Abstract

rationaleRescue/recovery work at the World Trade Center disaster site (WTC) caused a proximate decline in lung function in Fire Department of the City of New York firefighters. A subset of this cohort experienced an accelerated rate of lung function decline over 15 years of post-September 11, 2001 (9/11) follow-up.

objectivesTo determine if early postexposure blood leukocyte concentrations are biomarkers for subsequent FEV

methodsIndividual rates of forced expiratory volume in 1 second (FEV

resultsAccelerated FEV

conclusionsHigher post-9/11 blood neutrophil and eosinophil concentrations were associated with subsequent accelerated FEV

Indexed as

Airway ObstructionEosinophilsFirefightersForced Expiratory VolumeNeutrophilsAdultBiomarkersDisease ProgressionHumansLeukocyte CountLongitudinal StudiesLungMaleMiddle AgedOccupational ExposureOccupational HealthBiomarkerseosinophilslongitudinal studieslung injuryneutrophilsspirometry

Identifiers

PMID29099614
PMCPMC5802620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.