Evidence map›Paper›PMID 29099310›Full record

ReviewSmall GTPases2018

Rab proteins as major determinants of the Golgi complex structure.

Bruno Goud, Shijie Liu, Brian Storrie

Open access · bronzeAbstract readReview
In one paragraph

Review in Small GTPases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Pooled it
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  4. Garin3 regulates sperm-oocyte fusion and male fertility.Cellular and molecular life sciences : CMLS · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Bruno Gouda Institut Curie, PSL Research University, CNRS, UMR 144, Molecular Mechanisms of Intracellular Transport , Paris , France.
Shijie Liub Department of Physiology and Biophysics , University of Arkansas for Medical Sciences , Little Rock , USA.
Brian Storrieb Department of Physiology and Biophysics , University of Arkansas for Medical Sciences , Little Rock , USA.
University of Arkansas for Medical Sciences · USCentre National de la Recherche Scientifique · FR

Funding

Super-Res Holographic Microscopy to Advance Research on Golgi Apparatus FunctionU54GM105814 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI BROOKER, GARY, LUPASHIN, VLADIMIR V · 2013 to 2017
$2.1M
Role of Rab Proteins in Golgi Apparatus Structure and FunctionR01GM092960 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI STORRIE, BRIAN · 2011 to 2014
$1.2M
European Research Council 339847NIGMS NIH HHS R01 GM092960NIGMS NIH HHS U54 GM105814
6 · The paper itself

Abstract

GTP-ases of the Rab family (about 70 in human) are key regulators of intracellular transport and membrane trafficking in eukaryotic cells. Remarkably, almost one third associate with membranes of the Golgi complex and TGN (trans-Golgi network). Through interactions with a variety of effectors that include molecular motors, tethering complexes, scaffolding proteins and lipid kinases, they play an important role in maintaining Golgi architecture.

Indexed as

Amino Acid SequenceAnimalsGolgi ApparatusHumansrab GTP-Binding Proteinsrab GTP-Binding ProteinsGolgi apparatusintracellular transportmembrane homeostasisRab GTP-ases

Identifiers

PMID29099310
PMCPMC5902205
OpenAlexW2766412115

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.