Evidence map›Paper›PMID 29098573›Full record

ReviewCurrent osteoporosis reports2017

Diet and Exercise: a Match Made in Bone.

Hubertine M E Willems, Ellen G H M van den Heuvel, Ruud J W Schoemaker, Jenneke Klein-Nulend, Astrid D Bakker

Open access · hybridAbstract readReview
In one paragraph

Review in Current osteoporosis reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.

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  19. Bone Homeostasis and Gut Microbial-Dependent Signaling Pathways.Journal of microbiology and biotechnology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hubertine M E WillemsDepartment of Preventive Dentistry, Academic Center for Dentistry Amsterdam, Vrije Universiteit Amsterdam and University of Amsterdam, Amsterdam, The Netherlands.
Ellen G H M van den HeuvelFrieslandCampina, Amersfoort, The Netherlands.
Ruud J W SchoemakerFrieslandCampina, Amersfoort, The Netherlands.
Jenneke Klein-NulendDepartment of Oral Cell Biology, Academic Center for Dentistry Amsterdam, Vrije Universiteit Amsterdam and University of Amsterdam, Amsterdam Movement Sciences, Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, The Netherlands.
Astrid D BakkerDepartment of Oral Cell Biology, Academic Center for Dentistry Amsterdam, Vrije Universiteit Amsterdam and University of Amsterdam, Amsterdam Movement Sciences, Gustav Mahlerlaan 3004, 1081 LA, Amsterdam, The Netherlands. a.bakker@acta.nl.
FrieslandCampina (Netherlands) · NLVrije Universiteit Amsterdam · NLAcademic Center for Dentistry Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewMultiple dietary components have the potential to positively affect bone mineral density in early life and reduce loss of bone mass with aging. In addition, regular weight-bearing physical activity has a strong positive effect on bone through activation of osteocyte signaling. We will explore possible synergistic effects of dietary components and mechanical stimuli for bone health by identifying dietary components that have the potential to alter the response of osteocytes to mechanical loading. RECENT

findingsSeveral (sub)cellular aspects of osteocytes determine their signaling towards osteoblasts and osteoclasts in response to mechanical stimuli, such as the osteocyte cytoskeleton, estrogen receptor α, the vitamin D receptor, and the architecture of the lacunocanalicular system. Potential modulators of these features include 1,25-dihydroxy vitamin D

Indexed as

DietResistance TrainingBone and BonesBone DensityCalcitriolEstrogen Receptor alphaExerciseGenisteinHumansMechanotransduction, CellularOsteoblastsOsteoclastsOsteocytesReceptors, CalcitriolSignal TransductionVitamin KCalcitriolEstrogen Receptor alphaGenisteinReceptors, CalcitriolVitamin KBone healthDietDietary componentsNutritionOsteocytesPhysical activity

Identifiers

PMID29098573
PMCPMC5705732
OpenAlexW2765781661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.