Evidence map›Paper›PMID 29098432›Full record

Trial reportSurgical endoscopy2018

The influence of the different forms of appendix base closure on patient outcome in laparoscopic appendectomy: a randomized trial.

Samir Delibegović, Zlatan Mehmedovic

3 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Surgical endoscopy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04094480 naunknown statusnot on this mapstarted 2019, after this paper: background citation

A Comparison Between Non Absorbable Polymeric Clips and Endoloop Ligatures in Securing Appendicular Stump in Laparoscopic Appendicectomy at Assiut University Hospital

TypeinterventionalSponsorAssiut UniversityRan2019 to 2022Enrolled40ConditionsAppendicitisArmspolymeric non absorbable clips, endoloops
NCT05637554 naunknown statusnot on this mapstarted 2023, after this paper: background citation

Laparoscopic Clipping Versus Extracorporeal Ligation in Complicated Appendicitis Upper Egypt Overview, Prospective Randomized Comparative Study

TypeinterventionalSponsorAssiut UniversityRan2023 to 2024Enrolled40ConditionsAppendicitisArmsLaparoscopic appendectomy using clipping., Laparoscopic appendectomy using extracorporeal ligation to secure the base of the appendix.
NCT07689123 nacompletednot on this mapstarted 2025, after this paper: background citation

Evaluating the Outcome of Surgical Clip Versus Ligatures in Securing Base of Appendix in Laparoscopic Appendicectomy. A Randomized Controlled Single Blinded Study

TypeinterventionalSponsorUniversiti Sains MalaysiaRan2025 to 2026Enrolled64ConditionsAppendicitis (Diagnosis)Armssingle polymeric clip (XXL Click'aV Plus, Grena), suture ligature
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Comparison of three different methods for stump closure in laparoscopic appendectomy: Endoloop, Hem-o-lok clip, and endostapler.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2024
    Article
  10. Review
  11. Review
  12. Focus on identifying and closing knowledge gaps in acute appendicitis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Article
  13. Article
  14. Laparoscopic appendectomy, stump closure and endoloops: A meta-analysis.World journal of gastrointestinal surgery · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Samir DelibegovićDepartment of Colorectal Surgery, Clinic for Surgery, University Clinical Center, Tuzla, Bosnia and Herzegovina. delibegovic.samir@gmail.com.ORCID 0000-0003-0525-3288
Zlatan MehmedovicDepartment of Colorectal Surgery, Clinic for Surgery, University Clinical Center, Tuzla, Bosnia and Herzegovina.
University Clinical Center Tuzla · BAUniversity of Tuzla · BA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring laparoscopic appendectomy, the base of the appendix is usually secured by loop ligature or stapling device. Hem-o-lok and DS clips have been shown as alternative techniques. The aim of this study was to compare the clinical outcomes of various forms of securing the base of the appendix, in order to find the most suitable method. PATIENTS AND

methodsThe study included 120 patients with acute appendicitis randomly divided into four groups with 30 patients in each. In the first group, the base of the appendix was secured using an Endoloop, in the second group using a stapling device, in the third group using Hem-o-lok, and in the fourth group using a DS clip. The primary outcome was overall morbidity following securing the base of the appendix. Secondary outcomes were time of application and operative procedure, total length of stay, and surgical outcome.

resultsNo morbidity was recorded in any group. The time of application was significantly longer in the Endoloop group than in the Stapler (P < 0.0001), Hem-o-lok (P < 0.0001), and DS clips (P < 0.0001) groups. The time of application in the Stapler group was significantly shorter than in the Hem-o-lok (P < 0.0001) and the DS clips (P < 0.0001) groups. The time of the operative procedure was significantly longer in the Endoloop than in the Stapler group (P < 0.0001). The time of the operative procedure in the Stapler group was significantly shorter than in the DS clips group (P < 0.0001) but did not differ significantly from the Hem-o-lok group (P = 0.199). The time of the operative procedure in the Hem-o-lok group was significantly shorter than in the DS clips group (P = 0.044).

conclusionAll forms of closure of the appendix base are acceptable, but Hem-o-lok and DS clips have the best potential for further development, and will probably become the method of choice in securing the base of the appendix.

Indexed as

Acute DiseaseAdultAppendectomyAppendicitisFemaleFollow-Up StudiesHumansLaparoscopyLength of StayLigationMaleMiddle AgedOperative TimePostoperative ComplicationsSurgical StaplingTreatment OutcomeAcute appendicitisDS clipHem-o-lok clipLaparoscopic appendectomyLoop ligaturesStapling device

Identifiers

PMID29098432
OpenAlexW2765212284

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.