Evidence map›Paper›PMID 29098427›Full record

ArticleEuropean journal of nutrition2018

Association between egg consumption and cardiovascular disease events, diabetes and all-cause mortality.

Jing Guo, Ditte A Hobbs, John R Cockcroft, Peter C Elwood, Janet E Pickering, Julie A Lovegrove, David I Givens

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 8 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 8 syntheses or guidelines pooled it, 53 citations in OpenAlex.

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  17. Frequency of Egg Intake Associated with Mortality in Chinese Adults: An 8-Year Nationwide Cohort Study.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jing GuoInstitute for Food, Nutrition and Health, University of Reading, Reading, RG6 6AR, UK.
Ditte A HobbsHugh Sinclair Unit of Human Nutrition, University of Reading, Reading, RG6 6AR, UK.
John R CockcroftWales Heart Research Institute, Cardiff University, Cardiff, UK.
Peter C ElwoodDepartment of Primary Care and Public Health, Cardiff University, Cardiff, UK.
Janet E PickeringInstitute for Food, Nutrition and Health, University of Reading, Reading, RG6 6AR, UK.
Julie A LovegroveInstitute for Food, Nutrition and Health, University of Reading, Reading, RG6 6AR, UK. j.a.lovegrove@reading.ac.uk.
David I GivensInstitute for Food, Nutrition and Health, University of Reading, Reading, RG6 6AR, UK.
University of Reading · GBCardiff Metropolitan University · GBCardiff University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe association between egg consumption and cardiovascular disease (CVD) or type 2 diabetes (T2D) remains controversial. We investigated the association between egg consumption and risk of CVD (primary outcome), T2D and mortality in the Caerphilly prospective cohort study (CAPS) and National Diet and Nutritional Survey (NDNS).

methodsCAPS included 2512 men aged 45-59 years (1979-1983). Dietary intake, disease incidence and mortality were updated at 5-year intervals. NDNS included 754 adults aged 19-64 years from 2008 to 2012.

resultsMen free of CVD (n = 1781) were followed up for a mean of 22.8 years, egg consumption was not associated with new incidence of CVD (n = 715), mortality (n = 1028) or T2D (n = 120). When stroke (n = 248), MI (n = 477), heart failure (n = 201) were investigated separately, no associations between egg consumption and stroke and MI were identified, however, increased risk of stroke in subjects with T2D and/or impaired glucose tolerance (IGT, fasting plasma glucose ≥ 6.1 mmol/L), adjusted hazard ratios (95% CI) were 1.0 (reference), 1.09 (0.41, 2.88), 0.96 (0.37, 2.50), 1.39 (0.54, 3.56) and 2.87 (1.13, 7.27) for egg intake (n) of 0 ≤ n ≤ 1, 1 < n ≤ 2, 2 < n ≤ 3, 3 < n < 5, and n ≥ 5 eggs/wk, respectively (P = 0.01). In addition, cross-sectional analyses revealed that higher egg consumption was significantly associated with elevated fasting glucose in those with T2D and/or IGT (CAPS: baseline P = 0.02 and 5-year P = 0.04; NDNS: P = 0.05).

conclusionsHigher egg consumption was associated with higher blood glucose in subjects with T2D and/or IGT. The increased incidence of stroke with higher egg consumption among T2D and/or IGT sub-group warrants further investigation.

Indexed as

DietMortalityAdultBlood GlucoseBody Mass IndexCardiovascular DiseasesCross-Sectional StudiesDiabetes Mellitus, Type 2EggsFollow-Up StudiesGlucose IntoleranceHumansIncidenceMaleMiddle AgedNutrition AssessmentBlood GlucoseAll-cause mortalityCardiovascular diseaseEggsImpaired glucose toleranceType 2 diabetes

Identifiers

PMID29098427
PMCPMC6267402
OpenAlexW2765515243

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.