ArticleOxidative medicine and cellular longevity2017
Blood-Based Bioenergetic Profiling Reflects Differences in Brain Bioenergetics and Metabolism.
Article in Oxidative medicine and cellular longevity, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05948930 (Adaptive Working Memory and Physical Exercise Training to Improve Brain and Mitochondrial Function in MCI), which is not on this map. Cited by 49 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Adaptive Working Memory and Physical Exercise Training to Improve Brain and Mitochondrial Function in MCI
Who cites it
49 citing papers in PubMed, 65 citations in OpenAlex.
- Post-stroke fatigue as an indicator of underlying bioenergetics alterations.Journal of bioenergetics and biomembranes · 2019Trial
- Pollutant Exposure Shapes Mitochondrial Bioenergetics in a Wild Seabird.Environment & health (Washington, D.C.) · 2026Article
- Peripheral Mitochondrial Energetics are Associated with Cortical Neurophysiological Alterations in Alzheimer's Disease.medRxiv : the preprint server for health sciences · 2026Article
- Mitochondrial Dysfunction: The Cellular Bridge from Emotional Stress to Disease Onset: A Narrative Review.Biomolecules · 2026Review
- Circulating eNAMPT in Glaucoma: A Semi-Quantitative Plasma Analysis Before and After Nicotinamide Supplementation.Translational vision science & technology · 2026Article
- Brain-body mitochondrial distribution patterns lack coherence and point to tissue-specific regulatory mechanisms.Life metabolism · 2025Article
- Linking warmer nest temperatures to reduced body size in seabird nestlings: possible mitochondrial bioenergetic and proteomic mechanisms.The Journal of experimental biology · 2025Article
- Bioenergetic signatures of circulating blood cells as biosensors of metabolic health in food-producing animals.Frontiers in veterinary science · 2025Review
- Muscle Mitochondrial Bioenergetic Capacities Are Associated With Multimorbidity Burden in Older Adults: The Study of Muscle, Mobility and Aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Platelet Bioenergetics and Associations With Delirium and Coma in Patients With Sepsis: A Prospective Cohort Study.CHEST critical care · 2024Article
- Peripheral Blood Cells From Older Adults Exhibit Sex-Associated Differences in Mitochondrial Function.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Serum factors mediate changes in mitochondrial bioenergetics associated with diet and exercise interventions.GeroScience · 2024Article
- Mitochondria-Related Candidate Genes and Diagnostic Model to Predict Late-Onset Alzheimer's Disease and Mild Cognitive Impairment.Journal of Alzheimer's disease : JAD · 2024Article
- Brain and serum lipidomic profiles implicate Lands cycle acyl chain remodeling association withFrontiers in aging neuroscience · 2024Article
- Mitochondrial metabolism in blood more reliably predicts whole-animal energy needs compared to other tissues.iScience · 2023Article
- Muscle mitochondrial bioenergetic capacities is associated with multimorbidity burden in older adults: the Study of Muscle, Mobility and Aging (SOMMA).medRxiv : the preprint server for health sciences · 2023Article
- Could Alzheimer's disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?The American journal of clinical nutrition · 2023Review
- Type 2 Diabetes Related Mitochondrial Defects in Peripheral Mononucleated Blood Cells from Overweight Postmenopausal Women.Biomedicines · 2023Article
- Porcine blood cell and brain tissue energy metabolism: Effects of "early life stress".Frontiers in molecular biosciences · 2023Article
- Platelet polyphosphate and energy metabolism in professional male athletes (soccer players): A cross-sectional pilot study.Physiological reports · 2022Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
Blood-based bioenergetic profiling provides a minimally invasive assessment of mitochondrial health shown to be related to key features of aging. Previous studies show that blood cells recapitulate mitochondrial alterations in the central nervous system under pathological conditions, including the development of Alzheimer's disease. In this study of nonhuman primates, we focus on mitochondrial function and bioenergetic capacity assessed by the respirometric profiling of monocytes, platelets, and frontal cortex mitochondria. Our data indicate that differences in the maximal respiratory capacity of brain mitochondria are reflected by CD14+ monocyte maximal respiratory capacity and platelet and monocyte bioenergetic health index. A subset of nonhuman primates also underwent [
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.