Evidence map›Paper›PMID 29097936›Full record

ArticleContrast media & molecular imaging2017

Molecular Imaging to Predict Response to Targeted Therapies in Renal Cell Carcinoma.

Ingrid Leguerney, Ludovic de Rochefort, Marie Poirier-Quinot, Alexandre Ingels, Xavier Violas, Sandra Robin, Paule Opolon, Rose-Marie Dubuisson, Stéphanie Pitre-Champagnat, Philippe Robert and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Contrast media & molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ingrid LeguerneyIR4M, UMR 8081, Paris-Sud University, CNRS, Bâtiment 220, rue Ampère, 91405 Orsay Cedex, France.ORCID 0000-0001-9752-6719
Ludovic de RochefortIR4M, UMR 8081, Paris-Sud University, CNRS, Bâtiment 220, rue Ampère, 91405 Orsay Cedex, France.
Marie Poirier-QuinotIR4M, UMR 8081, Paris-Sud University, CNRS, Bâtiment 220, rue Ampère, 91405 Orsay Cedex, France.
Alexandre IngelsIR4M, UMR 8081, Paris-Sud University, CNRS, Bâtiment 220, rue Ampère, 91405 Orsay Cedex, France.
Xavier ViolasExperimental Imaging, MRI Unit, Research Division, Guerbet, 93600 Aulnay-sous-Bois, France.
Sandra RobinIR4M, UMR 8081, Paris-Sud University, CNRS, Bâtiment 220, rue Ampère, 91405 Orsay Cedex, France.
Paule OpolonGustave Roussy, 114 rue Edouard Vaillant, 94805 Villejuif Cedex, France.
Rose-Marie DubuissonIR4M, UMR 8081, Paris-Sud University, CNRS, Bâtiment 220, rue Ampère, 91405 Orsay Cedex, France.
Stéphanie Pitre-ChampagnatIR4M, UMR 8081, Paris-Sud University, CNRS, Bâtiment 220, rue Ampère, 91405 Orsay Cedex, France.
Philippe RobertExperimental Imaging, MRI Unit, Research Division, Guerbet, 93600 Aulnay-sous-Bois, France.
Nathalie LassauIR4M, UMR 8081, Paris-Sud University, CNRS, Bâtiment 220, rue Ampère, 91405 Orsay Cedex, France.
Université Paris-Sud · FRGuerbet (France) · FRInstitut Gustave Roussy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular magnetic resonance imaging targeted to an endothelial integrin involved in neoangiogenesis was compared to DCE-US and immunochemistry to assess the early response of three different therapeutic agents in renal cell carcinoma. Human A498 renal cells carcinoma was subcutaneously inoculated into 24 nude mice. Mice received either phosphate-buffered saline solution, sunitinib, everolimus, or bevacizumab during 4 days. DCE-US and molecular MRI targeting

Indexed as

AnimalsAntineoplastic AgentsBevacizumabCarcinoma, Renal CellCell Line, TumorEverolimusHeterograftsHumansIndolesMagnetic Resonance ImagingMaleMiceMolecular ImagingMolecular Targeted TherapyPyrrolesSunitinibAntineoplastic AgentsBevacizumabEverolimusIndolesPyrrolesSunitinib

Identifiers

PMID29097936
PMCPMC5612742
OpenAlexW2604624422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.