Evidence map›Paper›PMID 29097935›Full record

Trial reportContrast media & molecular imaging2017

An Individually Optimized Protocol of Contrast Medium Injection in Enhanced CT Scan for Liver Imaging.

Shi-Ting Feng, Hongzhang Zhu, Zhenpeng Peng, Li Huang, Zhi Dong, Ling Xu, Kun Huang, Xufeng Yang, Zhi Lin, Zi-Ping Li

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Contrast media & molecular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. An Individualized Contrast-Enhanced Liver Computed Tomography Imaging Protocol Based on Body Mass Index in 126 Patients Seen for Liver Cirrhosis.Medical science monitor : international medical journal of experimental and clinical research · 2021
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shi-Ting FengDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China.
Hongzhang ZhuDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China.
Zhenpeng PengDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China.
Li HuangDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China.
Zhi DongDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China.
Ling XuFaculty of Medicine and Dentistry, University of Western Australia, Perth, WA, Australia.
Kun HuangDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China.
Xufeng YangDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China.ORCID 0000-0001-7949-7440
Zhi LinDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China.ORCID 0000-0002-7745-5471
Zi-Ping LiDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, 58th, The Second Zhongshan Road, Guangzhou, Guangdong 510080, China.ORCID 0000-0003-0041-4062

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the effectiveness of a new individualized contrast medium injection protocol for enhanced liver CT scan. Methods: 324 patients who underwent plain and dual phase enhanced liver CT were randomly assigned to 2 groups: G1 ( Results: The mean contrast medium dose of G1 was statistically lower than that of G2. There were no significantly statistical differences in CT values and ΔHU of liver parenchyma during HAP, TLC values during HAP, and PVP between two groups. The CT values and ΔHU of liver parenchyma during PVP of G2 were significantly higher than those of G1. Two independent radiologists were both in substantial conformity in grading tumor conspicuity. Conclusion: Using the individually optimized injection protocol might reduce contrast medium dose without impacting on the imaging quality in enhanced liver CT.

Indexed as

Precision MedicineAdultAgedCarcinoma, HepatocellularContrast MediaFemaleHumansLiverLiver NeoplasmsMaleMiddle AgedContrast Media

Identifiers

PMID29097935
PMCPMC5612702

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.