ArticleWorld journal of gastroenterology2017
Trends and outcomes of pancreaticoduodenectomy for periampullary tumors: A 25-year single-center study of 1000 consecutive cases.
Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 50 citations in OpenAlex.
- Association between preoperative body mass index and postoperative short-term outcomes in patients undergoing pancreaticoduodenectomy: a multicenter study.Gland surgery · 2025Article
- High Geriatric Nutritional Risk Index Risk as a Predictor of Postoperative Complications and Early Mortality in Older Adult Patients Undergoing Pancreatoduodenectomy for Periampullary Malignancies.Journal of clinical medicine · 2025Article
- Modified reconstruction approach after pancreaticoduodenectomy optimizes postoperative outcomes: Results from a multivariate cohort analysis.Experimental and therapeutic medicine · 2024Article
- Readmissions Following Pancreaticoduodenectomy: Experience From a Tertiary Care Center in India.Cureus · 2024Article
- Initial Experience of Pancreaticoduodenectomy in a Newly Developed Hepato-Pancreato-Biliary Unit Serving in a Lower-Middle-Income Country.Journal of cancer & allied specialties · 2024Article
- Postoperative complications after pancreatoduodenectomy for malignancy: results from the Recurrence After Whipple's (RAW) study.BJS open · 2023Article
- Five-year follow-up after pancreatoduodenectomy performed for malignancy: A single-centre study.Annals of hepato-biliary-pancreatic surgery · 2023Article
- Development and Validation of Prognostic Nomograms for Periampullary Neuroendocrine Neoplasms: A SEER Database Analysis.Current oncology (Toronto, Ont.) · 2022Article
- Severity of Pancreatic Leak in Relation to Gut Restoration After Pancreaticoduodenectomy: The Role of the Roux-en-Y Configuration.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022Article
- Open pancreaticoduodenectomy: setting the benchmark of time to functional recovery.Langenbeck's archives of surgery · 2022Article
- 147 Pancreatoduodenectomies: a Single Center's Perspective into the Epidemiology and Surgical Outcomes of Periampullary and Pancreatic Cancers in South India.Journal of gastrointestinal cancer · 2021Observational
- Predictive nomogram for postoperative pancreatic fistula following pancreaticoduodenectomy: a retrospective study.BMC cancer · 2021Article
- Short internal pancreatic stent reduces pancreatic fistula in pancreatoduodenectomy.Langenbeck's archives of surgery · 2021Article
- Brief Report on a Novel Reconstruction Technique Following Pancreaticoduodenectomy.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2021Article
- Article
- Prognostic factors for long-term survival after pancreaticoduodenectomy for periampullary adenocarcinoma. A retrospective cohort study.Annals of medicine and surgery (2012) · 2020Article
- Three Thousand Consecutive Pancreaticoduodenectomies in a Tertiary Cancer Center: A Retrospective Observational Study.Journal of clinical medicine · 2020Article
- Twelve Hundred Consecutive Pancreato-Duodenectomies from Single Centre: Impact of Centre of Excellence on Pancreatic Cancer Surgery Across India.World journal of surgery · 2020Article
- Conditional Survival After Resection for Pancreatic Cancer: A Population-Based Study and Prediction Model.Annals of surgical oncology · 2020Article
- Observational
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Authors and funding
22 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the evolution, trends in surgical approaches and reconstruction techniques, and important lessons learned from performing 1000 consecutive pancreaticoduodenectomies (PDs) for periampullary tumors.
methodsThis is a retrospective review of the data of all patients who underwent PD for periampullary tumor during the period from January 1993 to April 2017. The data were categorized into three periods, including early period (1993-2002), middle period (2003-2012), and late period (2013-2017).
resultsThe frequency showed PD was increasingly performed after the year 2000. With time, elderly, cirrhotic and obese patients, as well as patients with uncinate process carcinoma and borderline tumor were increasingly selected for PD. The median operative time and postoperative hospital stay decreased significantly over the periods. Hospital mortality declined significantly, from 6.6% to 3.1%. Postoperative complications significantly decreased, from 40% to 27.9%. There was significant decrease in postoperative pancreatic fistula in the second 10 years, from 15% to 12.7%. There was a significant improvement in median survival and overall survival among the periods.
conclusionSurgical results of PD significantly improved, with mortality rate nearly reaching 3%. Pancreatic reconstruction following PD is still debatable. The survival rate was also improved but the rate of recurrence is still high, at 36.9%.
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