Evidence map›Paper›PMID 29097785›Full record

ReviewNature reviews. Neuroscience2017

The nano-architecture of the axonal cytoskeleton.

Christophe Leterrier, Pankaj Dubey, Subhojit Roy

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 83 papers.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

83 citing papers in PubMed.

  1. Article
  2. Histidine Ethylation by Histidine Methyltransferases SETD3 and METTL9.Chembiochem : a European journal of chemical biology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Consciousness, Microtubules, and the Axon Initial Segment.Integrative psychological & behavioral science · 2025
    Article
  10. Review
  11. Consciousness and spintronic coherence in microtubules.Communicative & integrative biology · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. In Vitro and In Vivo Analysis of Neuronal Polarity.Methods in molecular biology (Clifton, N.J.) · 2024
    Article

23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christophe LeterrierNeuroCyto, Neurobiologie des Interactions Cellulaires et Neurophysiopathologie (NICN) Unités Mixtes de Recherche (UMR) 7259, Aix Marseille Université, Centre National de la Recherche Scientifique (CNRS), 3344 Cedex 15, Marseille, France.
Pankaj DubeyDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison.
Subhojit RoyDepartment of Pathology and Laboratory Medicine, University of Wisconsin-Madison.

Funding

Slow axonal transport of cytosolic cargoes by dynamic-recruitment - a new trafficR01NS075233 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI ROY, SUBHOJIT · 2012 to 2023
$3.4M
Trafficking and Endosomal Sorting of APP and BACE-1R01AG048218 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI FRIEDL, ANDREAS · 2014 to 2018
$1.6M
A CRISPR-Cas9 screen to identify genetic modifiers of APP/BACE-1 interactionsR21AG052404 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI FRIEDL, ANDREAS · 2016 to 2017
$408k
NIA NIH HHS R01 AG048218NIA NIH HHS R21 AG052404NINDS NIH HHS R01 NS075233
6 · The paper itself

Abstract

The corporeal beauty of the neuronal cytoskeleton has captured the imagination of generations of scientists. One of the easiest cellular structures to visualize by light microscopy, its existence has been known for well over 100 years, yet we have only recently begun to fully appreciate its intricacy and diversity. Recent studies combining new probes with super-resolution microscopy and live imaging have revealed surprising details about the axonal cytoskeleton and, in particular, have discovered previously unknown actin-based structures. Along with traditional electron microscopy, these newer techniques offer a nanoscale view of the axonal cytoskeleton, which is important for our understanding of neuronal form and function, and lay the foundation for future studies. In this Review, we summarize existing concepts in the field and highlight contemporary discoveries that have fundamentally altered our perception of the axonal cytoskeleton.

Indexed as

AnimalsArchitectureAxonal TransportAxonsCytoskeletonHumansMicroscopy, ElectronNeurons

Identifiers

PMID29097785

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.