Evidence map›Paper›PMID 29097774›Full record

ArticleScientific reports2017

Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling.

Amanda E Au, Marion Lebois, Starling A Sim, Ping Cannon, Jason Corbin, Pradnya Gangatirkar, Craig D Hyland, Diane Moujalled, Angelika Rutgersson, Fatme Yassinson and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. C-Cbl regulates c-MPL receptor trafficking and its internalization.Journal of cellular and molecular medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 2 countries.

Amanda E AuThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Marion LeboisThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Starling A SimThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Ping CannonThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Jason CorbinThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Pradnya GangatirkarThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Craig D HylandThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Diane MoujalledThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Angelika RutgerssonThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Fatme YassinsonThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Benjamin T KileThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.ORCID 0000-0002-8836-8947
Kylie D MasonThe University of Melbourne, Faculty of Medicine, Dentistry and Health Sciences, Melbourne, VIC, Australia.
Ashley P NgThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Warren S AlexanderThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia.
Emma C JosefssonThe Walter and Eliza Hall Institute of Medical Research, 1 G Royal Parade, VIC 3052, Australia. josefsson@wehi.edu.au.ORCID 0000-0001-6478-5204
Walter and Eliza Hall Institute of Medical Research · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombopoietin (TPO) is the master cytokine regulator of megakaryopoiesis. In addition to regulation of megakaryocyte and platelet number, TPO is important for maintaining proper hematopoietic stem cell (HSC) function. It was previously shown that a number of lymphoid genes were upregulated in HSCs from Tpo

Indexed as

LymphopoiesisSignal TransductionAnimalsB-LymphocytesCell CycleFemaleLymphoid Progenitor CellsMaleMiceMice, Inbred C57BLThrombopoietinThrombopoietin

Identifiers

PMID29097774
PMCPMC5668349
OpenAlexW2766059821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.