Evidence map›Paper›PMID 29097763›Full record

ArticleScientific reports2017

Efficacy of an Adenoviral Vectored Multivalent Centralized Influenza Vaccine.

Amy Lingel, Brianna L Bullard, Eric A Weaver

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 27 citations in OpenAlex.

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  11. A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Amy LingelSchool of Biological Sciences, Nebraska Center for Virology, University of Nebraska, Lincoln, USA.
Brianna L BullardSchool of Biological Sciences, Nebraska Center for Virology, University of Nebraska, Lincoln, USA.
Eric A WeaverSchool of Biological Sciences, Nebraska Center for Virology, University of Nebraska, Lincoln, USA. eweaver2@unl.edu.
University of Nebraska–Lincoln · US

Funding

Foundation Immunogens for Influenza VaccinesR01AI097241 · NIAID · UNIVERSITY OF NEBRASKA LINCOLN · PI WEAVER, ERIC A · 2012 to 2015
$1.6M
NIAID NIH HHS R01 AI097241
6 · The paper itself

Abstract

Mice were immunized with Adenovirus expressing the H1-con, H2-con, H3-con and H5-con HA consensus genes in combination (multivalent) and compared to mice immunized with the traditional 2010-2011 FluZone and FluMist seasonal vaccines. Immunized mice were challenged with 10-100 MLD

Indexed as

AdenoviridaeAnimalsFemaleHemagglutinin Glycoproteins, Influenza VirusHumansInfluenza A virusInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H3N2 SubtypeInfluenza A Virus, H5N1 SubtypeInfluenza, HumanInfluenza VaccinesMiceMice, Inbred BALB COrthomyxoviridae InfectionsVaccinationHemagglutinin Glycoproteins, Influenza VirusInfluenza Vaccines

Identifiers

PMID29097763
PMCPMC5668234
OpenAlexW2765110249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.