Evidence map›Paper›PMID 29097670›Full record

ArticleScientific reports2017

The genetic variation in the R1a clade among the Ashkenazi Levites' Y chromosome.

Doron M Behar, Lauri Saag, Monika Karmin, Meir G Gover, Jeffrey D Wexler, Luisa Fernanda Sanchez, Elliott Greenspan, Alena Kushniarevich, Oleg Davydenko, Hovhannes Sahakyan and 12 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. The Yemeni genetic structure revealed by the Y chromosome STRs.Forensic science, medicine, and pathology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Doron M BeharEstonian Biocentre, Tartu, 51010, Estonia. behardm@genebygene.com.
Lauri SaagEstonian Biocentre, Tartu, 51010, Estonia.
Monika KarminEstonian Biocentre, Tartu, 51010, Estonia.ORCID 0000-0001-9827-5579
Meir G GoverIndependent Genetic Genealogy Researcher, Savyon, 5690500, Israel.
Jeffrey D Wexlerlevitedna.org, Los Angeles, 90045, California, USA.
Luisa Fernanda SanchezGenomic Research Center, Gene by Gene, Houston, 77008, Texas, USA.
Elliott GreenspanGenomic Research Center, Gene by Gene, Houston, 77008, Texas, USA.
Alena KushniarevichEstonian Biocentre, Tartu, 51010, Estonia.
Oleg DavydenkoInstitute of Genetics and Cytology, National Academy of Sciences of Belarus, 220072, Minsk, Belarus.
Hovhannes SahakyanEstonian Biocentre, Tartu, 51010, Estonia.ORCID 0000-0003-1596-2838
Levon YepiskoposyanLaboratory of Ethnogenomics, Institute of Molecular Biology of National Academy of Sciences, Yerevan, 0014, Armenia.
Alessio BoattiniDepartment of Biological, Geological and Environmental Sciences, University of Bologna, Bologna, 40126, Italy.
Stefania SarnoDepartment of Biological, Geological and Environmental Sciences, University of Bologna, Bologna, 40126, Italy.
Luca PaganiEstonian Biocentre, Tartu, 51010, Estonia.
Shai CarmiBraun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem, 9112102, Israel.
Shay TzurBraun School of Public Health and Community Medicine, The Hebrew University of Jerusalem, Jerusalem, 9112102, Israel.
Ene MetspaluEstonian Biocentre, Tartu, 51010, Estonia.
Concetta BormansGenomic Research Center, Gene by Gene, Houston, 77008, Texas, USA.
Karl SkoreckiRambam Health Care Campus, Haifa, 3109601, Israel.
Mait MetspaluEstonian Biocentre, Tartu, 51010, Estonia.ORCID 0000-0003-3099-9161
Siiri RootsiEstonian Biocentre, Tartu, 51010, Estonia.
Richard VillemsEstonian Biocentre, Tartu, 51010, Estonia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 300,000 men around the globe self-identify as Ashkenazi Levites, of whom two thirds were previously shown to descend from a single male. The paucity of whole Y-chromosome sequences precluded conclusive identification of this ancestor's age, geographic origin and migration patterns. Here, we report the variation of 486 Y-chromosomes within the Ashkenazi and non-Ashkenazi Levite R1a clade, other Ashkenazi Jewish paternal lineages, as well as non-Levite Jewish and non-Jewish R1a samples. Cumulatively, the emerging profile is of a Middle Eastern ancestor, self-affiliating as Levite, and carrying the highly resolved R1a-Y2619 lineage, which was likely a minor haplogroup among the Hebrews. A star-like phylogeny, coalescing similarly to other Ashkenazi paternal lineages, ~1,743 ybp, suggests it to be one of the Ashkenazi paternal founders; to have expanded as part of the overall Ashkenazi demographic expansion, without special relation to the Levite affiliation; and to have subsequently spread to non-Ashkenazi Levites.

Indexed as

Evolution, MolecularChromosomes, Human, YGene FrequencyGenetic VariationHaplotypesHumansJewsMalePhylogeny

Identifiers

PMID29097670
PMCPMC5668307

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.