ArticleJournal of the American Society of Nephrology : JASN2018
Clinical Decision Support for In-Hospital AKI.
Article in Journal of the American Society of Nephrology : JASN, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04530448 (Coronavirus Induced Acute Kidney Injury), which is not on this map. Cited by 221 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Coronavirus Induced Acute Kidney Injury: Prevention Using Urine Alkalinization
Who cites it
221 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- STARDaki: a consensus-based STARD extension for standardized reporting of diagnostic accuracy in acute kidney injury.Intensive care medicine · 2026Pooled it
- The influence of electronic AKI alert on prognosis of adult hospitalized patients: a systematic review and meta-analysis.Critical care (London, England) · 2025Pooled it
- The role of urinary Dickkopf-3 in the prediction of acute kidney injury: a systematic review meta-analysis.International urology and nephrology · 2023Pooled it
- Performance of urinary C-C motif chemokine ligand 14 for the prediction of persistent acute kidney injury: a systematic review and meta-analysis.Critical care (London, England) · 2023Pooled it
- Effect of clinical decision support systems on clinical outcome for acute kidney injury: a systematic review and meta-analysis.BMC nephrology · 2021Pooled it
- Automated Electronic Alert for the Care and Outcomes of Adults With Acute Kidney Injury: A Randomized Clinical Trial.JAMA network open · 2024Trial
- A randomized clinical trial assessing the effect of automated medication-targeted alerts on acute kidney injury outcomes.Nature communications · 2023Trial
- Electronic health record alerts for acute kidney injury: multicenter, randomized clinical trial.BMJ (Clinical research ed.) · 2021Trial
- In-hospital electronic monitoring system approaches to epidemiologic investigation and predictive modeling of contrast-induced acute kidney injury.Renal failure · 2026Article
- Metabolic memory in the kidney: how lactate and lactylation drive the path from acute injury to chronic disease.Renal failure · 2026Review
- AKI as a systemic syndrome and its impact on other organ systems.Critical care (London, England) · 2026Review
- Kidney-Targeted Cilastatin Nanoparticles Inhibit DPEP1-Mediated Ferroptosis for Acute Kidney Injury Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Risk analysis and warning model of post-noncardiac surgery acute kidney injury: A retrospective observational study.Medicine · 2026Observational
- SLC38A6 expression in renal tubular cells accelerates cisplatin-induced acute kidney injury by promoting cell apoptosis.The FEBS journal · 2026Article
- Large language model driven multicenter prediction and explainable risk attribution of acute kidney injury.Nature communications · 2026Article
- Impact of an Artificial Intelligence-Powered Clinical Decision Support System for Acute Kidney Injury Prevention in the Intensive Care Unit: Single-Center Uncontrolled Before-and-After Implementation Study.JMIR formative research · 2026Article
- Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes Attenuate Renal Fibrosis by Suppressing Fibroblast Activation via the INHBA/PI3K/AKT Pathway.Pediatric discovery · 2026Article
- Single-cell Stereo-seq reveals regulatory mechanisms driving regeneration of injured proximal tubules during AKI.Nature communications · 2026Article
- Dual Roles and Therapeutic Prospects of Proximal Tubular Epithelial Cell Senescence in Acute Kidney Injury.Biomolecules · 2026Review
- Prediction of acute kidney injury in patients with acute pesticide poisoning using the PKIP score.Scientific reports · 2026Article
161 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
AKI carries a significant mortality and morbidity risk. Use of a clinical decision support system (CDSS) might improve outcomes. We conducted a multicenter, sequential period analysis of 528,108 patients without ESRD before admission, from October of 2012 to September of 2015, to determine whether use of a CDSS reduces hospital length of stay and in-hospital mortality for patients with AKI. We compared patients treated 12 months before (181,696) and 24 months after (346,412) implementation of the CDSS. Coprimary outcomes were hospital mortality and length of stay adjusted by demographics and comorbidities. AKI was diagnosed in 64,512 patients (12.2%). Crude mortality rate fell from 10.2% before to 9.4% after CDSS implementation (odds ratio, 0.91; 95% confidence interval [95% CI], 0.86 to 0.96;
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Registered trials
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