Evidence map›Paper›PMID 29097567›Full record

ArticleThe Veterinary record2017

Survival in 76 cats with epilepsy of unknown cause: a retrospective study.

Arlette Cornelia Szelecsenyi, Urs Giger, Lorenzo Golini, Ian Mothersill, Paul R Torgerson, Frank Steffen

Open access · greenAbstract read
In one paragraph

Article in The Veterinary record, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  5. Epilepsy in British Shorthair cats in Sweden.Journal of feline medicine and surgery · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Arlette Cornelia SzelecsenyiDepartment of Clinical Veterinary Medicine, Small Animal Clinic, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Urs GigerSchool of Veterinary Medicine, Section of Medical Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Lorenzo GoliniDepartment of Clinical Veterinary Medicine, Small Animal Clinic, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Ian MothersillDepartment of Clinical Neurophysiology, Swiss Epilepsy Centre, Laboratory of EEG and Long Term Monitoring, Zürich, Switzerland.
Paul R TorgersonSection of Veterinary Epidemiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Frank SteffenDepartment of Small Animals, Neurology Service, VetSuisse Faculty - University of Zurich, Zurich, Switzerland.
University of Zurich · CHSwiss Epilepsy Center · CHUniversity of Pennsylvania · US

Funding

Referral Ctr-Animal models of human genetic diseaseP40OD010939 · OD · UNIVERSITY OF PENNSYLVANIA · PI CASAL, MARGRET L · 2012 to 2023
$7.9M
NIH HHS P40 OD010939
6 · The paper itself

Abstract

Survival of cats with epilepsy of unknown cause (EUC) has not been reported. Seizure semiology and its relationship to treatment outcome and survival was studied in a population of 76 cats. A questionnaire for seizure semiology was developed based on experimental data. Seizure semiology was characterised by owner interviews at least one year after discharge. Seizures were classified as (1) primary generalised and (2) focal without and (3) with secondary generalisation. Median age at seizure onset was four (range 0.3-18) years. One-third of cats with EUC presented with primary generalised seizures and 78 per cent of those with initially focal seizures progressed to secondary generalised seizures. Clinical signs of generalised seizures included sudden onset of loss of consciousness and tonic-clonic seizures, while cats with focal seizures had unilateral signs. Antiepileptic drug (AED) therapy was initiated in 62 cats. Complete remission rate was 42 per cent and the median survival time was 3.2 (range 1-11) years with or without AED, and 91 per cent were still alive at the time of interview. Neither semiology nor seizure type predicted survival, response to treatment and outcome in cats with EUC. A seizure-free status of more than 12 months was observed in 79 per cent of cats without AED.

Indexed as

AnimalsAnticonvulsantsCat DiseasesCatsEpilepsyFemaleMaleRetrospective StudiesSeizuresSurvival AnalysisTreatment OutcomeAnticonvulsantsepilepsy of unknown causefelineoutcomesemiologysurvival

Identifiers

PMID29097567
PMCPMC5748884
OpenAlexW2765133242

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.