Evidence map›Paper›PMID 29097422›Full record

ArticleCancer immunology research2018

Intratumoral CD8

Brendan L Horton, Jason B Williams, Alexandra Cabanov, Stefani Spranger, Thomas F Gajewski

Abstract read
In one paragraph

Article in Cancer immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

117 citing papers in PubMed.

  1. Trial
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  11. Article
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  13. Biomedicines · 2025
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Batf3Cell reports · 2024
    Article
  19. Review
  20. Article

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Brendan L HortonDepartment of Pathology, University of Chicago, Chicago, Illinois.
Jason B WilliamsDepartment of Pathology, University of Chicago, Chicago, Illinois.
Alexandra CabanovThe Committee on Immunology, University of Chicago, Chicago, Illinois.
Stefani SprangerDepartment of Pathology, University of Chicago, Chicago, Illinois.
Thomas F GajewskiDepartment of Pathology, University of Chicago, Chicago, Illinois. tgajewsk@medicine.bsd.uchicago.edu.

Funding

VIRAL ONCOLOGY CORE FACILITYP30CA014599 · NCI · UNIVERSITY OF CHICAGO · PI MARK W. LINGEN · 1985 to 2026
$122.1M
INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007090 · NIAID · UNIVERSITY OF CHICAGO · PI Peter Aidan Savage · 1985 to 2026
$11.7M
Multi-Disciplinary Training Grant in Cancer ResearchT32CA009594 · NCI · UNIVERSITY OF CHICAGO · PI KAY F MACLEOD, Scott A. Oakes · 1989 to 2026
$11.5M
Overcoming resistance to anti-PD1 immunotherapyR35CA210098 · NCI · UNIVERSITY OF CHICAGO · PI THOMAS F GAJEWSKI · 2017 to 2026
$10.4M
EGR2 in T cell toleranceR01CA161005 · NCI · UNIVERSITY OF CHICAGO · PI GAJEWSKI, THOMAS F · 2012 to 2016
$1.6M
NCI NIH HHS P30 CA014599NCI NIH HHS R01 CA161005NCI NIH HHS R35 CA210098NCI NIH HHS T32 CA009594NIAID NIH HHS T32 AI007090
6 · The paper itself

Abstract

Subsets of human tumors are infiltrated with tumor antigen-specific CD8

Indexed as

AnimalsAntigens, NeoplasmAntineoplastic Agents, ImmunologicalApoptosisBiomarkersCD8-Positive T-LymphocytesCell Line, TumorDisease Models, AnimalDisease ProgressionDNA DamageGene Expression ProfilingHumansLymphocytes, Tumor-InfiltratingMelanoma, ExperimentalMiceMice, KnockoutAntigens, NeoplasmAntineoplastic Agents, ImmunologicalBiomarkersTumor Necrosis Factor Receptor Superfamily, Member 9

Identifiers

PMID29097422
PMCPMC5754226

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.