Evidence map›Paper›PMID 29097418›Full record

ArticleSexually transmitted infections2018

Prevalence and treatment outcomes of routine

Adriane Wynn, Doreen Ramogola-Masire, Ponatshego Gaolebale, Neo Moshashane, Ontiretse Sickboy, Sofia Duque, Elizabeth Williams, Klara Doherty, Jeffrey D Klausner, Chelsea Morroni

Open access · greenAbstract read
In one paragraph

Article in Sexually transmitted infections, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Effect of antenatalSexually transmitted infections · 2025
    Trial
  3. Article
  4. Article
  5. Clinical Manifestation and Epidemiological Finding ofIranian journal of public health · 2022
    Review
  6. Article
  7. Article
  8. Sexually transmitted infections in pregnant women from sub-Saharan Africa.Southern African journal of infectious diseases · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Point-by-Point Progress: Gonorrhea Point of Care Tests.Expert review of molecular diagnostics · 2020
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Adriane WynnFielding School of Public Health, University of California, Los Angeles, California, USA.ORCID 0000-0001-8067-3616
Doreen Ramogola-MasireDepartment of Medicine, University of Botswana, Gaborone, Botswana.
Ponatshego GaolebaleDepartment of Obstetrics and Gynecology, Princess Marina Hospital, Gaborone, Botswana.
Neo MoshashaneBotswana - UPenn Partnership, University of Pennsylvania, Gaborone, Botswana.
Ontiretse SickboyBotswana - UPenn Partnership, University of Pennsylvania, Gaborone, Botswana.
Sofia DuqueBotswana - UPenn Partnership, University of Pennsylvania, Gaborone, Botswana.
Elizabeth WilliamsBarts Health, NHS Trust, London, UK.
Klara DohertyBotswana - UPenn Partnership, University of Pennsylvania, Gaborone, Botswana.
Jeffrey D KlausnerFielding School of Public Health, University of California, Los Angeles, California, USA.
Chelsea MorroniDepartment of Medicine, University of Botswana, Gaborone, Botswana.
University of Botswana · BWUniversity of California, Los Angeles · USBarts Health NHS Trust · GB

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAPHAEL J LANDOVITZ · 1997 to 2026
$53.5M
University of California Launching Future Leaders in Global Health Research Training ProgramD43TW009343 · FIC · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CRAIG R COHEN, Sung-Jae Lee · 2017 to 2026
$14.7M
UCLA/RAND HEALTH SERVICES RESEARCH TRAINING PROGRAMT32HS000046 · AHRQ · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI EISENBERG, DANIEL · 1992 to 2024
$8.7M
Training Program in Substance Use, HIV and Related InfectionsT32DA023356 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Natasha Martin, Steffanie A Strathdee · 2007 to 2026
$7.8M
FIC NIH HHS D43 TW009343NIDA NIH HHS T32 DA023356NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

objectives

methodsWe conducted a prospective study in the antenatal clinic at Princess Marina Hospital in Gaborone, Botswana. We offered pregnant women who were 18 years or older and less than 35 weeks of gestation, CT, NG and TV testing using self-collected vaginal swabs. Testing was conducted using a GeneXpert® CT/NG and TV system. Those who tested positive were given directly observed antibiotic therapy and asked to return for a test of cure. We determined the prevalence of infections, uptake of treatment and proportion cured. The relationships between positive STI test and participant characteristics were assessed.

resultsWe enrolled 400 pregnant women. Fifty-four (13.5%) tested positive for CT, NG and/or TV: 31 (8%) for CT, 5 (1.3%) for NG and 21 (5%) for TV. Among those who tested positive, 74% (40) received same-day, in person results and treatment. Among those who received delayed results (6), 67% (4) were treated. Statistical comparisons showed that being unmarried and HIV infected were positively association CT, NG and/or TV infection. Self-reported STI symptoms were not associated with CT, NG and/or TV infection.

conclusionThe prevalence of CT, NG and/or TV was high, particularly among women with HIV infection. Among women with CT, NG and/or TV infection, those who received same-day results were more likely to be treated than those who received delayed results. More research is needed on the costs and benefits of integrating highly sensitive and specific STI testing into antenatal care in Southern Africa.

Indexed as

AdultAnti-Bacterial AgentsBotswanaChlamydia InfectionsCoinfectionDirectly Observed TherapyFemaleGonorrheaHIV InfectionsHumansPregnancyPregnancy Complications, InfectiousPregnant PeoplePrenatal CarePrevalenceProspective StudiesAnti-Bacterial Agentsafricachlamydia trachomatisneisseria gonorrhoeapregnancytrichomonas

Identifiers

PMID29097418
PMCPMC6117829
OpenAlexW2766322292

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.