Evidence map›Paper›PMID 29097359›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2018

Customization of biliopancreatic limb length to modulate and sustain antidiabetic effect of gastric bypass surgery.

A Pal, D B Rhoads, A Tavakkoli

Abstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  5. Article
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  7. Article
  8. Portal milieu and the interplay of multiple antidiabetic effects after gastric bypass surgery.American journal of physiology. Gastrointestinal and liver physiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A PalDepartment of Surgery, Brigham and Women's Hospital , Boston, Massachusetts.
D B RhoadsHarvard Medical School Boston, Massachusetts.
A TavakkoliDepartment of Surgery, Brigham and Women's Hospital , Boston, Massachusetts.

Funding

Surgical Modulation of Intestinal Nutrient TransportR01DK084064 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI TAVAKKOLI, ALI · 2011 to 2015
$1.9M
NIDDK NIH HHS R01 DK084064
6 · The paper itself

Abstract

Although Roux-en-Y Gastric Bypass (RYGB) remains the most effective treatment for obesity and type 2 diabetes (T2D), many patients fail to achieve remission, or relapse. Increasing intestinal limb lengths of RYGB may improve outcomes, but the mechanistic basis for this remains unclear. We hypothesize biliopancreatic (BP) limb length modulates the antidiabetic effect of RYGB. Rats underwent RYGB with a 20-cm (RYGB-20cm) or 40-cm (RYGB-40cm) BP limb and were compared with control animals. After 2 and 4 wk, portal and systemic blood was sampled during intestinal glucose infusion. Portosystemic gradient was used to calculate intestinal glucose utilization (G

Indexed as

AnimalsBiomarkersBlood GlucoseEatingEnergy MetabolismGastric BypassGastrointestinal HormonesGene Expression Regulation, EnzymologicIntestinal AbsorptionIntestine, SmallLiverMaleRats, Sprague-DawleyTime FactorsWeight LossBiomarkersBlood GlucoseGastrointestinal Hormonesdiabetesincretin

Identifiers

PMID29097359
PMCPMC5866424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.