Evidence map›Paper›PMID 29096573›Full record

Observational studyScandinavian journal of primary health care2017

Drug-related problems and changes in drug utilization after medication reviews in nursing homes in Oslo, Norway.

Amura Francesca Fog, Gunnar Kvalvaag, Knut Engedal, Jørund Straand

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Scandinavian journal of primary health care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  8. Drug-Related Problems and Polypharmacy in Nursing Home Residents: A Cross-Sectional Study.International journal of environmental research and public health · 2022
    Observational
  9. Review
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Amura Francesca Foga Nursing Home Agency , Oslo , Norway.
Gunnar Kvalvaaga Nursing Home Agency , Oslo , Norway.
Knut Engedalc Norwegian National Advisory Unit for Aging and Health , Vestfold County Hospital HF, Toensberg and Oslo University Hospital , Oslo , Norway.
Jørund Straandb Department of General Practice, Institute of Health and Society , University of Oslo , Oslo , Norway.
University of Oslo · NOOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe describe the drug-related problems (DRPs) identified during medication reviews (MRs) and the changes in drug utilization after MRs at nursing homes in Oslo, Norway. We explored predictors for the observed changes.

designObservational before-after study.

settingForty-one nursing homes.

interventionMRs performed by multidisciplinary teams during November 2011 to February 2014. SUBJECTS: In all, 2465 long-term care patients.

main outcome measuresDRPs identified by explicit criteria (STOPP/START and NORGEP) and drug-drug interaction database; interventions to resolve DRPs; drug use changes after MR.

resultsA total of 6158 DRPs were identified, an average of 2.6 DRPs/patient, 2.0 for regular and 0.6 for pro re nata (prn) drugs. Of these patients, 17.3% had no DRPs. The remaining 82.7% of the patients had on average 3.0 DRPs/patient. Use of unnecessary drugs (43.5%), excess dosing (12.5%) and lack of monitoring of the drug use (11%) were the most frequent DRPs. Opioids and psychotropic drugs were involved in 34.4% of all DRPs. The mean number of drugs decreased after the MR from 6.8 to 6.3 for regular drugs and from 3.0 to 2.6 for prn drugs. Patients with DRPs experienced a decrease of 1.1 drugs after MR (0.5 for regular and 0.6 for prn drugs). The reduction was most pronounced for the regular use of antipsychotics, antidepressants, hypnotics/sedatives, diuretics, antithrombotic agents, antacid drugs; and for prn use of anxiolytics, opioids, hypnotics/sedatives, metoclopramide and NSAIDs.

conclusionThe medication review resulted in less drug use, especially opioids and psychotropic drugs.

Indexed as

Drug MonitoringDrug PrescriptionsDrug UtilizationInappropriate PrescribingLong-Term CareMedical OveruseNursing HomesAdultAgedAged, 80 and overAnalgesics, OpioidDrug InteractionsDrug-Related Side Effects and Adverse ReactionsDrug Utilization ReviewFemaleHomes for the AgedAnalgesics, OpioidPsychotropic DrugsdiscontinuationDrug-related problemselderlymedication reviewnursing home

Identifiers

PMID29096573
PMCPMC5730030
OpenAlexW2765171789

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.