Evidence map›Paper›PMID 29096563›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2018

Preconditioning with hydrogen sulfide prevents bone cancer pain in rats through a proliferator-activated receptor gamma/p38/Jun N-terminal kinase pathway.

Li Zhuang, Ke Li, Gaowei Wang, Tao Shou, Chunlin Gao, Yong Mao, Mingliang Bao, Mingli Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Li Zhuang1 The Department of Palliative Medicine, The Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Yunnan Palliative Medicine Research Center, Yunnan 650118, China.
Ke Li2 The Second Department of Medicine, the Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Yunnan 650118, China.
Gaowei Wang3 Department of Medical Service, the Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Yunnan 650118, China.
Tao Shou4 Department of Oncology, the First People's Hospital of Yunnan Province, Yunnan 650032, China.
Chunlin Gao2 The Second Department of Medicine, the Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Yunnan 650118, China.
Yong Mao5 Department of Pain Medicine, the Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Yunnan 650118, China.
Mingliang Bao2 The Second Department of Medicine, the Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Yunnan 650118, China.
Mingli Zhao6 The Third Department of Medicine, the Third Affiliated Hospital of Kunming Medical University Yunnan Tumor Hospital, Yunnan 650118, China.
Kunming Medical University · CNFirst People's Hospital of Yunnan Province · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone cancer pain (BCP) is a severe type of hyperpathic pain occurring with primary bone tumors or advanced cancers which metastasize to bones. BCP can detrimentally reduce quality of life and presents a challenge to modern medicine. Studies have shown that exogenous H

Indexed as

AdultAnimalsBone NeoplasmsDisease Models, AnimalFemaleHumansHydrogen SulfideJNK Mitogen-Activated Protein KinasesMaleMiddle Agedp38 Mitogen-Activated Protein KinasesPainPPAR gammaRats, WistarSignal TransductionHydrogen SulfideJNK Mitogen-Activated Protein Kinasesp38 Mitogen-Activated Protein KinasesPPAR gammaPPAR gamma, ratBone cancer painhydrogen sulfideinflammatory cytokinesmicrogliapreconditioningproliferator-activated receptor gamma/p38/Jun N-terminal kinase pathway

Identifiers

PMID29096563
PMCPMC5788158
OpenAlexW2765757489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.