ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2017
Intermittent theta-burst stimulation induces correlated changes in cortical and corticospinal excitability in healthy older subjects.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Methodological Choices Matter: A Systematic Comparison of TMS-EEG Studies Targeting the Primary Motor Cortex.Human brain mapping · 2024Pooled it
- Pharmacological adjuncts and transcranial magnetic stimulation-induced synaptic plasticity: a systematic review.Journal of psychiatry & neuroscience : JPNPooled it
- Nil effects of μ-rhythm phase-dependent burst-rTMS on cortical excitability in humans: A resting-state EEG and TMS-EEG study.PloS one · 2018Trial
- The Influence of M1 and DLPFC iTBS on BCI Performance: A TMS and fNIRS Study.Translational stroke research · 2026Article
- The Supplementary Motor Area as a Flexible Hub Mediating Behavioral and Neuroplastic Changes in Motor Sequence Learning: A TMS and TMS-EEG Study.Neuroscience bulletin · 2025Article
- Monitoring Changes in TMS-Evoked EEG and EMG Activity During 1 Hz rTMS of the Healthy Motor Cortex.eNeuro · 2024Article
- No effect of whole-hand water flow stimulation on skill acquisition and retention during sensorimotor adaptation.Frontiers in human neuroscience · 2024Article
- Effect of regional intrinsic activity following two kinds of theta burst stimulation on precuneus.Human brain mapping · 2023Article
- Using TMS-EEG to assess the effects of neuromodulation techniques: a narrative review.Frontiers in human neuroscience · 2023Review
- Intermittent Theta Burst Stimulation Increases Natural Oscillatory Frequency in Ipsilesional Motor Cortex Post-Stroke: A Transcranial Magnetic Stimulation and Electroencephalography Study.Frontiers in aging neuroscience · 2022Article
- Intermittent Theta Burst Stimulation to the Primary Motor Cortex Reduces Cortical Inhibition: A TMS-EEG Study.Brain sciences · 2021Article
- Human Theta Burst Stimulation Combined with Subsequent Electroacupuncture Increases Corticospinal Excitability.Evidence-based complementary and alternative medicine : eCAM · 2020Article
- Non-invasive Brain Stimulation: Probing Intracortical Circuits and Improving Cognition in the Aging Brain.Frontiers in aging neuroscience · 2018Review
- Reproducibility of cortical response modulation induced by intermittent and continuous theta-burst stimulation of the human motor cortex.Brain stimulationArticle
- Cortical markers of PAS-induced long-term potentiation and depression in the motor system: A TMS-EEG Registered Report.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveWe studied the correlation between motor evoked potentials (MEPs) and early TMS-evoked EEG potentials (TEPs) from single-pulse TMS before and after intermittent Theta Burst Stimulation (iTBS) to the left primary motor cortex (M1) in 17 healthy older participants.
methodsTMS was targeted to the hand region of M1 using a MRI-guided navigated brain stimulation system and a figure-of-eight biphasic coil. MEPs were recorded from the right first dorsal interosseous muscle using surface EMG. TEPs were extracted from a 61-channel EEG recording. Participants received 90 single TMS pulses at 120% of resting motor threshold before and after iTBS.
resultsAcross all participants, the change in N15-P30 TEP and MEP amplitudes were significantly correlated (r=0.69; p<0.01). Average TEP responses did not change significantly after iTBS, whereas MEP amplitudes showed a significant increase.
conclusionsChanges in corticospinal reactivity and cortical reactivity induced by iTBS are related. However, the effect of iTBS on TEPs, unlike MEPs, is not straightforward. SIGNIFICANCE: Our findings help elucidate the relationship between changes in cortical and corticospinal excitability in healthy older individuals. Going forward, TEPs may be used to evaluate the effects of theta-burst stimulation in non-motor brain regions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.