ArticleEuropean psychiatry : the journal of the Association of European Psychiatrists2018
Are comorbid anxiety disorders a risk factor for suicide attempts in patients with mood disorders? A two-year prospective study.
Article in European psychiatry : the journal of the Association of European Psychiatrists, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed.
- Mixed features and suicide attempts in youth depression: a six-month follow-up study.BMC psychiatry · 2026Article
- Development and validation of a nomogram for suicide attempts in patients with first-episode drug-naïve major depressive disorder.Frontiers in psychiatry · 2024Article
- Molecular Changes Associated with Suicide.International journal of molecular sciences · 2023Review
- Vitamin D and suicidality: a Chinese early adolescent cohort and Mendelian randomization study.Epidemiology and psychiatric sciences · 2023Article
- Prevalence and influencing factors of suicide in first-episode and drug-naive young major depressive disorder patients with impaired fasting glucose: a cross-sectional study.Frontiers in psychiatry · 2023Article
- Perceived stress and life satisfaction among elderly migrants in China: A moderated mediation model.Frontiers in psychology · 2022Article
- The association of clinical correlates, metabolic parameters, and thyroid hormones with suicide attempts in first-episode and drug-naïve patients with major depressive disorder comorbid with anxiety: a large-scale cross-sectional study.Translational psychiatry · 2021Article
- The Association Between the 5Cs and Anxiety-Insights From Three Countries: Portugal, Slovenia, and Spain.Frontiers in psychology · 2021Article
- Mechanisms Underlying the Anti-Suicidal Treatment Potential of Buprenorphine.Advances in drug and alcohol research · 2021Article
- A Naturalistic Study of Youth Referred to a Tertiary Care Facility for Acute Hypomanic or Manic Episode.Brain sciences · 2020Article
- Understanding the Complex of Suicide in Depression: from Research to Clinics.Psychiatry investigation · 2020Article
- Development of an early-warning system for high-risk patients for suicide attempt using deep learning and electronic health records.Translational psychiatry · 2020Article
- Are quantity and content of psychiatric interventions associated with suicide? A case-control study of a Swedish sample.BMC psychiatry · 2020Article
- Modelling suicide ideation from beep to beep: Application of network analysis to ecological momentary assessment data.Internet interventions · 2019Article
- The longitudinal association between lifetime mental disorders and first onset or recurrent suicide ideation.BMC psychiatry · 2019Article
- Well-being in major depression and social phobia with and without comorbidity.International journal of clinical and health psychology : IJCHPArticle
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10 authors.
Funding
Abstract
backgroundComorbid anxiety disorders have been considered a risk factor for suicidal behavior in patients with mood disorders, although results are controversial. The aim of this two-year prospective study was to determine if lifetime and current comorbid anxiety disorders at baseline were risk factors for suicide attempts during the two-year follow-up.
methodsWe evaluated 667 patients with mood disorders (504 with major depression and 167 with bipolar disorder) divided in two groups: those with lifetime comorbid anxiety disorders (n=229) and those without (n=438). Assessments were performed at baseline and at 3, 12, and 24 months. Kaplan-Meier survival analysis and log-rank test were used to evaluate the relationship between anxiety disorders and suicide attempts. Cox proportional hazard regression was performed to investigate clinical and demographic variables that were associated with suicide attempts during follow-up.
resultsOf the initial sample of 667 patients, 480 had all three follow-up interviews. During the follow-up, 63 patients (13.1%) attempted suicide at least once. There was no significant difference in survival curves for patients with and without comorbid anxiety disorders (log-rank test=0.269; P=0.604). Female gender (HR=3.66, P=0.001), previous suicide attempts (HR=3.27, P=0.001) and higher scores in the Buss-Durkee Hostility Inventory (HR=1.05, P≤0.001) were associated with future suicide attempts.
conclusionsOur results suggest that comorbid anxiety disorders were not risk factors for suicide attempts. Further studies were needed to determine the role of anxiety disorders as risk factors for suicide attempts.
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