Evidence map›Paper›PMID 29096054›Full record

ArticleMagnetic resonance in medicine2018

Comparison of ferumoxytol-based cerebral blood volume estimates using quantitative R

Leonardo A Rivera-Rivera, Tilman Schubert, Gesine Knobloch, Patrick A Turski, Oliver Wieben, Scott B Reeder, Kevin M Johnson

Abstract readComparative Study
In one paragraph

Article in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Aqueous-stable Mn(II)-MOF nanoparticles with highJournal of materials chemistry. B · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Leonardo A Rivera-RiveraDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Tilman SchubertDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Gesine KnoblochDepartment of Radiology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Patrick A TurskiDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Oliver WiebenDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Scott B ReederDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Kevin M JohnsonDepartment of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
University of Wisconsin–Madison · US

Funding

Accelerated Neuro-MRA Using Compressed Sensing and Constrained ReconstructionR01NS066982 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, KEVIN MICHAEL, TURSKI, PATRICK ALAN · 2010 to 2018
$2.7M
Evolution of Quantitative MRI Biomarkers of Metabolic Syndrome During PubertyK24DK102595 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2014 to 2018
$927k
NIDDK NIH HHS K24 DK102595NINDS NIH HHS R01 NS066982
6 · The paper itself

Abstract

purposeCerebral perfusion is commonly assessed clinically with dynamic susceptibility contrast MRI using a bolus injection of gadolinium-based contrast agents, resulting in semi-quantitative values of cerebral blood volume (CBV). Steady-state imaging with ferumoxytol allows estimation of CBV with the potential for higher precision and accuracy. Prior CBV studies have focused on the signal disrupting T2* effects, but ferumoxytol also has high signal-enhancing T

methodsChanges in R

resultsR

conclusionsCBV measurements were successfully derived using a combined approach of R

Indexed as

Cerebrovascular CirculationMagnetic Resonance ImagingAdultBlood VolumeBrainCerebral Blood VolumeContrast MediaFemaleFerrosoferric OxideGadoliniumHemodynamicsHumansImage Processing, Computer-AssistedLeast-Squares AnalysisMaleMiddle AgedContrast MediaFerrosoferric OxideGadoliniumcerebral blood volumeferumoxytolgray matterR1R2*white matter

Identifiers

PMID29096054
PMCPMC5843511
OpenAlexW2765367036

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.