Evidence map›Paper›PMID 29096052›Full record

ArticleMagnetic resonance in medicine2018

TOPPE: A framework for rapid prototyping of MR pulse sequences.

Jon-Fredrik Nielsen, Douglas C Noll

Open access · greenAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 49 citations in OpenAlex.

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  19. A vendor-neutral EPI sequence for hyperpolarizedMagnetic resonance in medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jon-Fredrik NielsenDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
Douglas C NollDepartment of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan, USA.
University of Michigan–Ann Arbor · US

Funding

Improved Functional MRI Using Balanced SSFP and Parallel TransmissionR21EB012674 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NIELSEN, JON-FREDRIK · 2011 to 2012
$404k
Toward layer-specific BOLD fMRI in human cortex at 3T using 3D zoomed-EPI and smallip fast-recovery imagingR21EB019653 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI NIELSEN, JON-FREDRIK · 2015 to 2016
$401k
NIBIB NIH HHS R21 EB012674NIBIB NIH HHS R21 EB019653
6 · The paper itself

Abstract

purposeTo introduce a framework for rapid prototyping of MR pulse sequences.

methodsWe propose a simple file format, called "TOPPE", for specifying all details of an MR imaging experiment, such as gradient and radiofrequency waveforms and the complete scan loop. In addition, we provide a TOPPE file "interpreter" for GE scanners, which is a binary executable that loads TOPPE files and executes the sequence on the scanner. We also provide MATLAB scripts for reading and writing TOPPE files and previewing the sequence prior to hardware execution. With this setup, the task of the pulse sequence programmer is reduced to creating TOPPE files, eliminating the need for hardware-specific programming. No sequence-specific compilation is necessary; the interpreter only needs to be compiled once (for every scanner software upgrade). We demonstrate TOPPE in three different applications: k-space mapping, non-Cartesian PRESTO whole-brain dynamic imaging, and myelin mapping in the brain using inhomogeneous magnetization transfer.

resultsWe successfully implemented and executed the three example sequences. By simply changing the various TOPPE sequence files, a single binary executable (interpreter) was used to execute several different sequences.

conclusionThe TOPPE file format is a complete specification of an MR imaging experiment, based on arbitrary sequences of a (typically small) number of unique modules. Along with the GE interpreter, TOPPE comprises a modular and flexible platform for rapid prototyping of new pulse sequences. Magn Reson Med 79:3128-3134, 2018. © 2017 International Society for Magnetic Resonance in Medicine.

Indexed as

AlgorithmsBrainHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingSignal-To-Noise Ratioopen MRIopen sourceplatform-independentpulse sequence programmingpulse sequence prototyping

Identifiers

PMID29096052
PMCPMC6134833
OpenAlexW2766394323

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.